Over 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we discuss the potential and challenges of humanized mouse models for developing effective and affordable therapies and vaccines, which are desperately needed to combat these diseases.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038630PMC
http://dx.doi.org/10.1016/j.chom.2009.06.006DOI Listing

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