Objective: To compare procalcitonin measurements between semi-quantitative and quantitative assays.

Method: Procalcitonin was measured with the PCT-Q and the Kryptor assays in a pediatric emergency department.

Results: Among the 359 pairs of results, 103 had discordant results. The linear weighted kappa was 0.44 (95% CI 0.36, 0.51). The concordant/discordant results distribution varied depending on the laboratory technician (p=0.018).

Conclusion: Agreement between procalcitonin measured semi-quantitatively and quantitatively was moderate. This is probably due to a subjective interpretation of the assay result.

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http://dx.doi.org/10.1016/j.clinbiochem.2009.07.005DOI Listing

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