The Authors report the case of intra-thyroid metastasis from uveal malignant melanoma, diagnosed by fine needle aspiration biopsy, 15 years after surgical treatment of the primary tumour. The site is very unusual as illustrated by a review of the literature, and confirms the extreme heterogeneity that sometimes the natural history of this pathology shows. The critical analysis of diagnostic reliability of the cytological techniques, proves their usefulness in the differential diagnosis of every suspicious mass.
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