Objective: To report two cases of successful monozygotic twin pregnancies in women undergoing infertility treatment and to review possible etiologic factors.
Design: Case report and review of the literature.
Setting: University of Toronto-affiliated infertility clinic.
Patient(s): A 43-year-old woman and a 44-year-old woman with history of secondary infertility.
Intervention(s): In vitro fertilization and ET.
Main Outcome Measure(s): Monozygotic twin pregnancy.
Result(s): Delivery of two sets of monozygotic twins.
Conclusion(s): The only identified potential risk factors for monozygotic twins are maternal age and assisted reproductive technologies. Both patients reported here were aged >40 years and underwent assisted reproduction procedures, including high-dose gonadotropin stimulation, embryo culture, and, in case 2, intracytoplasmic sperm injection plus assisted hatching.
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| http://dx.doi.org/10.1016/j.fertnstert.2009.05.085 | DOI Listing |
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