An unprecedented transfer of a thiocyanate (-SCN) group from aroyl/acyl isothiocyanate to alkyl or benzylic bromide is observed in the presence of a tertiary amine. This process is most effective when the bromomethyl proton is less acidic, while the presence of a more acidic proton gives 1,3-oxathiol-2-ylidine and other related products.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ol901561j | DOI Listing |
Publication Analysis
Top Keywords
acyl-isothiocyanates efficient
4
efficient thiocyanate
4
thiocyanate transfer
4
transfer reagents
4
reagents unprecedented
4
unprecedented transfer
4
transfer thiocyanate
4
thiocyanate -scn
4
-scn group
4
group aroyl/acyl
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!