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Background: Chronic lymphocytic leukemia (CLL) is the most prevalent type of leukemia in adults, characterized by the accumulation of mature-appearing, immunologically dysfunctional B lymphocytes in the blood, bone marrow, and secondary lymphoid organs. Oral manifestations of CLL are infrequent and less documented. The authors present a case of CLL in remission with multiple lesions of the palatal mucosa and a literature review of all reported cases of oral manifestations of CLL.
View Article and Find Full Text PDFClinical Reasoning: An Unusual Etiology of Lumbosacral Plexopathy in a Patient With HIV.
Neurology
November 2024
From the Departments of Neurology (B.M., A.J.S., N.B.K., R.S.S.), and Pathology (M.S.U.), Nizam's Institute of Medical Sciences.
Article Synopsis
- A case study describes a patient with uncontrolled diabetes who initially showed symptoms resembling diabetic lumbosacral radiculoplexus neuropathy (DLRPN), including lower limb pain, weakness, and sensory loss.
- The patient was also found to be HIV-1 positive, prompting further diagnostic testing that revealed abnormal results in cerebrospinal fluid (CSF) and a nerve biopsy that suggested an alternative diagnosis.
- The study emphasizes the need for thorough diagnostic evaluations in cases where atypical presentations of neuropathy occur, especially when multiple medical conditions are present.
Acute Coronary Syndrome as an Unusual Initial Presentation of T-Prolymphocytic Leukemia: A Case Report and Review of the Literature.
Case Rep Hematol
August 2024
Department of Oncology, Hematology, Immune-Oncology and Rheumatology University Hospital Bonn, Bonn, Germany.
T-prolymphocytic leukaemia (T-PLL) is the most common mature T-cell leukaemia in Central Europe and is often manifested by rapidly increasing lymphocytosis, marked bone marrow infiltration and splenomegaly. In 10-15% of cases, the diagnosis is made by incidental findings in otherwise asymptomatic patients. Here we report a case of T-PLL that initially became symptomatic due to the presence of acute coronary syndrome (ACS).
View Article and Find Full Text PDFT-PLL Presenting with an Indolent Course.
Case Rep Hematol
July 2024
Department of Medicine Faculty of Medicine Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
T-cell prolymphocytic leukemia (T-PLL) is a rare, mature T-cell leukemia which usually presents with aggressive behavior. We report an asymptomatic T-PLL patient diagnosed by clinical features, lymphocyte morphology, and flow cytometry. Incidentally, she was found to have lymphocytosis and lymphadenopathy.
View Article and Find Full Text PDFIncidental diagnosis of cardiac fibroma in an infant with acute viral bronchiolitis.
Rev Paul Pediatr
May 2024
Hospital Pequeno Príncipe (HPP), Curitiba, PR, Brasil.
Article Synopsis
- Pediatric cardiac tumors are uncommon, with the majority being benign, and cardiac fibroma is notably the second most common type after rhabdomyoma.
- A case of a 5-month-old boy with acute viral bronchiolitis revealed incidental findings of a cardiac fibroma via various diagnostic tests, including echocardiogram and cardiac catheterization, leading to its confirmation.
- Treatment typically involves surgery or heart transplantation, especially for cases with significant dysfunction, and accurate characterization of the tumor is crucial for determining the best therapeutic strategy.
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