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[Characteristics of postmortem changes in the brain].
Sud Med Ekspert
December 2024
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov, Moscow, Russia.
The study aimed to analyze the literature data on postmortem changes in the brain and their use to determine the time since death. The earliest manifestations of brain cell autolysis are detected by electron microscopy (15-20 minutes after death). The longer the postmortem period, the more morphofunctional changes in the brain are revealed by histological, histochemical, and immunohistochemical studies.
View Article and Find Full Text PDFBrief report: effects of methylphenidate on the light adapted electroretinogram.
Doc Ophthalmol
December 2024
Behavioural and Brain Sciences Unit, Population Policy and Practice Programme, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
Purpose: To explore changes in the electroretinogram (ERG) following methylphenidate use in attention-deficit/hyperactivity disorder (ADHD).
Methods: Light adapted ERGs were recorded in five individuals (3 male and 2 female, age range 13.6-21.
Mobile Stroke Unit Management in Patients With Acute Ischemic Stroke Eligible for Intravenous Thrombolysis.
JAMA Neurol
December 2024
Memorial Hermann Hospital, Houston, Texas.
Article Synopsis
- Clinical trials indicate that using a mobile stroke unit (MSU) for prehospital management can lead to better outcomes for acute ischemic stroke patients who may need thrombolysis, but real-world data is limited.
- This study aimed to compare the effects of prehospital MSU management versus standard emergency services (EMS) on patient disability levels at the time of hospital discharge.
- The analysis included over 19,000 patients treated across multiple hospitals, revealing that those managed in an MSU had improved functional outcomes compared to those receiving standard EMS care.*
Slips of the tongue in patients with Gilles de la Tourette syndrome.
Neurol Res Pract
May 2024
Center of Brain, Behavior and Metabolism, University of Lübeck, Marie-Curie-Straße, Building 66, 23562, Lübeck, Germany.
Background: Motor and vocal tics are the main symptom of Gilles de la Tourette-syndrome (GTS). A particular complex vocal tic comprises the utterance of swear words, termed coprolalia. Since taboo words are socially inappropriate, they are normally suppressed by people, which implies cognitive control processes.
View Article and Find Full Text PDFAn inclusive multivariate approach to neural localization of language components.
Brain Struct Funct
June 2024
University of Maryland, College Park, MD, USA.
To determine how language is implemented in the brain, it is important to know which brain areas are primarily engaged in language processing and which are not. Existing protocols for localizing language are typically univariate, treating each small unit of brain volume as independent. One prominent example that focuses on the overall language network in functional magnetic resonance imaging (fMRI) uses a contrast between neural responses to sentences and sets of pseudowords (pronounceable nonwords).
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