Background: The aim of the present study was to assess the prevalence of depression in subjects before starting a weight-reduction programme.
Methods: The study group involved 173 obese subjects aged 47.0 +/- 16.5 years, body mass index (BMI) 36.1 +/- 6.3, weight 96.2 +/- 18.3 kg. The body weight and height were measured and BMI was calculated. Beck's Depression Inventory (BDI) was used for the evaluation of depressive symptoms.
Results: Severe depression was diagnosed in 84 subjects (mean BMI 37.5 +/- 6.3, mean weight 98.1 +/- 17.6 kg, age 48.7 +/- 16.0, 22.2 +/- 1.6 points), mild depression was diagnosed in 65 subjects (mean BMI 34.7 +/- 4.8, mean weight 95.3 +/- 18.1 kg, age 45.9 +/- 16.6; 10.8 +/- 2.0 points), and 24 subjects (mean BMI 35.0 +/- 8.7, mean weight 92.2 +/- 21.1 kg, age 44.0 +/- 17.5, 6.5 +/- 0.5 points) did not have depression. We observed differences in BMI between subjects without depression and severe depression (p < 0.05) and between mild and severe depression. We did not observe differences of age and body mass between these subgroups. Correlations between weight, BMI and BDI score were found in all subjects.
Conclusion: Depression often accompanies obesity. The depression levels increased in morbidly obese persons in comparison to moderately obese patients.
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http://dx.doi.org/10.1177/0020764008095930 | DOI Listing |
Best Pract Res Clin Anaesthesiol
September 2024
Department of Anesthesiology, University Hospital Basel, Basel, Switzerland.
The issue of obesity continues to reach new levels globally, affecting individuals across the age continuum. Obesity in pregnancy is associated with myriad comorbidities which may negatively impact the fetus, particularly dysfunctional labor and failure to progress ending in unplanned cesarean delivery. Neuraxial anesthesia represents the gold standard for cesarean delivery anesthesia and is increasingly beneficial for obese patients due to the risk of difficult airway.
View Article and Find Full Text PDFAfr J Reprod Health
December 2024
Department of Obstetrics, Xiaolan People's Hospital of Zhongshan (The Fifth People's Hospital of Zhongshan), Zhongshan,528415, China.
Elevated serum uric acid (SUA) levels in pregnancy are linked to adverse outcomes, including preterm birth, preeclampsia, and low birth weight. To assess the predictive value of SUA levels in early pregnancy for adverse pregnancy outcomes (APOs). A cohort of 4,240 pregnant women admitted for delivery from January 2021 to December 2022 was analyzed.
View Article and Find Full Text PDFInt J Numer Method Biomed Eng
January 2025
College of Chemistry and Life Science, Beijing University of Technology, Beijing, China.
The accurate non-invasive detection and estimation of central aortic pressure waveforms (CAPW) are crucial for reliable treatments of cardiovascular system diseases. But the accuracy and practicality of current estimation methods need to be improved. Our study combines a meta-learning neural network and a physics-driven method to accurately estimate CAPW based on personalized physiological indicators.
View Article and Find Full Text PDFNanomedicine (Lond)
January 2025
Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA.
Aim: To develop pH (pHe)-triggered membrane adhesive nanoliposome (pHTANL) of CD40a to enhance anti-tumor activity in pancreatic cancer while reducing systemic toxicity.
Materials And Methods: A small library of nanoliposomes (NL) with various lipid compositions were synthesized to prepare pH (pHe)-triggered membrane adhesive nanoliposome (pHTANL). Physical and functional characterization of pHTANL-CD40a was performed via dynamic light scattering (DLS), Transmission Electron Microscopy (TEM), confocal microscopy, and flow cytometry.
J Eval Clin Pract
February 2025
California State University Monterey Bay, Seaside, California, USA.
Rationale: Obesity is an increasing medical issue not responding well to behavioural treatments beyond their initial weeks/months.
Aims And Objectives: Before suggesting surgical or pharmacological interventions, medical professionals might consider referrals to cost-effective, community-based behavioural treatments if stronger theoretical/empirical bases were demonstrated. Thus, evaluation of such is warranted.
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