Background: Interpretative commenting is an important activity of the clinical diagnostic laboratory. We describe a study of interpretative commenting abilities among senior laboratory professionals in the Asia-Pacific region and Africa.
Methods: Five sets of laboratory results reflecting common and important problems encountered in clinical chemistry were distributed at 4-weekly intervals to 31 registered participants from countries in the Asia-Pacific region and Africa. Participants were asked to attach an interpretative comment to the results assuming that the requesting doctor had asked for an interpretation of the result.
Results: Twelve pathologists and 19 scientists from seven countries registered to participate and the overall reply rate was approximately 50% for the five cases. The quality of the comments returned by participants was diverse and some reflected incorrect or misleading interpretation and advice.
Conclusions: While interpretative commenting is an important laboratory activity, the results of this study suggest that there is room for improvement in the quality of interpretative comments offered by senior laboratory professionals, even for commonly reported results relating to most prevalent and important public health conditions. Interpretative commenting should be formally taught during training of pathologists and scientists, and continuing professional development in this area is required for the provision of a quality interpretative service.
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http://dx.doi.org/10.1515/CCLM.2009.225 | DOI Listing |
The kinetically-derived maximal dose (KMD) is defined as the maximum external dose at which kinetics are unchanged relative to lower doses, e.g., doses at which kinetic processes are not saturated.
View Article and Find Full Text PDFClin Drug Investig
January 2025
Department of Medicine, Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Perelman School of Medicine, 423 Guardian Drive, Philadelphia, PA, 19104, USA.
Purpose: The REDUCE-IT randomized trial demonstrated a cardiovascular benefit of icosapent ethyl (IPE) but also raised potential safety signals for atrial fibrillation (AF) and serious bleeding. We aimed to evaluate the real-world safety of IPE versus mixed omega-3 polyunsaturated fatty acid (OM-3) formulations.
Methods: This retrospective active comparator new-user cohort study compared rates of new-onset AF and major bleeding (MB) among adult new users of IPE versus OM-3 in 2020-2024 US Veterans Affairs data.
JASA Express Lett
January 2025
Schmalhausen Institute of Zoology of National Academy of Sciences of Ukraine, Bohdana Khmel'nyts'koho Street, 15, Kyiv 02000, Ukraine.
Dolphin and porpoise detections by the F-POD are not independent: Implications for sympatric species monitoring, Cosentino, Marcolin, Griffiths, Sánchez-Camí, and Tougaard [(2024). JASA Express Lett. 4, 031202] address a significant issue, the reliability of the discrimination of dolphins and porpoises in recordings of their acoustic clicks by F-POD loggers, but unfortunately present a misleading interpretation of the process and results.
View Article and Find Full Text PDFHealthcare (Basel)
December 2024
School of Social Sciences, University of Westminster, London W1B 2HW, UK.
: Body dissatisfaction among women has been on the rise, prompting an urgent need to understand the underlying factors influencing their body image. This study explores the perceptions and influencing factors of body image among women in Greek society. : Six in-depth interviews were conducted and analyzed using Interpretative Phenomenological Analysis.
View Article and Find Full Text PDFJ Autism Dev Disord
January 2025
Department of Clinical Psychology, School of Health in Social Science, Medical School, University of Edinburgh, Teviot Place, Central Campus, Edinburgh, EH8 9AG, UK.
Much of the current autism and gender literature has been based within a medical deficiency model; where both are seen as deficiencies rather than differences. However, there is currently minimal knowledge about the experiences of being an autistic adolescent who is both assigned female at birth and has gender dysphoria (GD), whilst even less is known about their experiences of social identity, self-concept and resilience. This study aims to explore experiences of GD with a particular focus on identity and resilience to promote parent and healthcare staff understanding; particularly around gender-affirming care, to foster positive mental health outcomes.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!