AI Article Synopsis
- Adult obesity is linked to depression, particularly in women, but the relationship between the two—whether one causes the other—is still uncertain.
- Researchers assessed depression levels in 63 obese women using Beck's questionnaire, then categorized them into groups based on mood status: no depression, mild depression, and severe depression.
- Despite these classifications, there were no significant differences in inflammation markers (TNF-alpha, leptin, IL-6) or other health metrics related to body composition among the mood groups, suggesting that these factors do not impact depression levels in obese women.
Article Abstract
Adult obesity has been associated with depression, especially in women. Whether depression leads to obesity or obesity causes depression is unclear. Chronic inflammation is observed in obesity and depression. In 63 obese women without additional diseases depression level was assessed with the Beck's questionnaire. After evaluation of depression level study group was divided into groups according to the mood status (A--without depression, B-mild depression, and C--severe depression), and serum concentration of TNF-alpha, sTNFs, leptin, and IL-6 were measured by ELISA. No differences in age, body mass, BMI, and body composition were observed in study groups. We did not observe differences of serum concentrations of TNF-alpha, sTNFRs, leptin, and IL-6 between subgroup A and subgroups B and C. It seems that circulating adipokines did not exert influence on depression levels in obese women.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705765 | PMC |
| http://dx.doi.org/10.1155/2009/439107 | DOI Listing |
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