Group C streptococci rarely cause severe disease in humans. The authors report a 15-year-old girl with group C streptococcal pneumonia. No immune deficiencies were detected in our patient and investigation of virulence factors including emmL, sag A, spegg and smeZ genes failed to reveal insight into why the isolated group C streptococcal strain was so virulent. Fourteen other reports of primary group C streptococcal pneumonia were reviewed.
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