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Prompt Diagnosis and Treatment of Japanese Spotted Fever with an Atypical Triad of Clinical Symptoms: A Case Report.
Infect Drug Resist
November 2024
Department of Infectious Disease, The General Hospital of Western Theater Command, Chengdu, 610083 People's Republic of China.
Japanese spotted fever (JSF) is a neglected and potentially fatal infectious disease. Delays in diagnosis and treatment of JSF are important causes of poor prognosis. We report a case of JSF in a 75-year-old farmer who, following autumn field work in Sichuan, China, presented with an atypical triad of clinical symptoms: high fever, petechial rash, and notably no eschar.
View Article and Find Full Text PDFA case of rapidly progressive unilateral non-nephrogenic hemorrhagic bullous calciphylaxis responding to systemic sodium thiosulfate therapy.
Wounds
October 2024
UMass Chan Medical School, Department of Dermatology, Worcester, MA.
Background: Calciphylaxis is a rare and life-threatening condition characterized by cutaneous necrosis resulting from vessel calcification and thrombosis. Commonly associated with end-stage renal disease and hyperparathyroidism, calciphylaxis presents as retiform purpura evolving into necrotic eschars.
Case Report: This report details an atypical case of non-nephrogenic unilateral bullous calciphylaxis in a 71-year-old female, emphasizing the importance of considering calciphylaxis in the differential diagnosis of bullous disorders.
Challenging Neurological Presentation: Scrub Typhus with Meningoencephalitis and Multiple Cranial Nerve Involvement.
Neurol Clin Neurosci
September 2024
Department of Neurology, University Hospital "12 de Octubre", Madrid, Spain.
A 40-year-old male farmer from rural West Bengal, India, presented with fever, headaches, seizure, eschar, and palsy of left cranial nerves VII, VIII, IX, and X as a rare clinical manifestation of scrub typhus. Positive IgM enzyme-linked immunosorbent assay tests in serum and cerebrospinal fluid confirmed the diagnosis, with brain magnetic resonance imaging showing meningoencephalitis findings. Treatment with steroids and doxycycline led to neurological improvement.
View Article and Find Full Text PDFOmadacycline in the treatment of scrub typhus: Three case reports.
World J Clin Cases
September 2024
Department of Emergency Medicine, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an 223000, Jiangsu Province, China.
Article Synopsis
- Scrub typhus is an infectious disease spread by chigger bites, and omadacycline is a new antibiotic that shows promise against various pathogens but has limited use for this infection.
- A case study examined patients with scrub typhus who presented symptoms like fever, ulcers, and lymph node swelling, confirming the infection through next-generation sequencing before treating with omadacycline.
- Following treatment with omadacycline, patients experienced symptom relief within two days without any negative side effects, indicating its potential as an alternative treatment for scrub typhus.
Ocular inflammation in tsutsugamushi disease - a case report.
Eur J Ophthalmol
September 2024
Department of Ophthalmology, Cathay General Hospital, Taipei, Taiwan.
A 64-year-old male, working at a mountain site in Taitung County, suffered from primary open angle glaucoma (POAG) post trabeculectomy with well-controlled intraocular pressure (IOP) in both eyes (OU). He presented with headache accompanied by red eyes (OU) for 10 days. Physical examination revealed fever up to 38.
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