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Free Flap Reconstruction of the Oropharynx.
Facial Plast Surg Clin North Am
February 2025
Department of Otorhinolaryngology-Head and Neck Surgery, Hospital of the University of Pennsylvania, 5th Floor Ravdin, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address:
Reconstruction of the oropharynx plays a critical role in preserving quality of life after surgical resection of oropharyngeal carcinoma. Free tissue is one of several reconstructive options, which can closely approximate native oropharyngeal anatomy and lead to favorable functional outcomes in carefully selected patients. Here, the authors provide an overview of the indications, treatment options, functional outcomes, potential complications, and future considerations for free flap reconstruction of the oropharynx.
View Article and Find Full Text PDF3D modeling of anterior 2/3rds glossectomy reconstruction: A volume based donor site evaluation.
Oral Oncol
October 2024
Department of Otolaryngology - Head and Neck Surgery, University of Pittsburgh, Medical Center, Pittsburgh, PA, USA. Electronic address:
Objective: Anterior 2/3rds glossectomy results in significant patient morbidity due to speech and swallowing impairment. Microvascular free flap reconstruction compensates for large volume defects. Flap volume is based on the adipose content of the donor site and varies by patient body mass index (BMI) and donor site location.
View Article and Find Full Text PDFLow-rank prior-based Fast-RPCA for clutter filtering and noise suppression in non-contrast ultrasound microvascular imaging.
Ultrasonics
August 2024
The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, China. Electronic address:
Article Synopsis
- Accurate real-time separation of blood signals from noise is essential for effective ultrasound microvascular imaging, but current methods like SVD and RPCA have limitations.
- This study introduces a new method called low-rank prior-based fast RPCA (LP-fRPCA), which enhances noise filtering and operational efficiency by combining a low-rank constraint with an improved algorithm.
- In tests on phantom and rabbit kidney models, LP-fRPCA outperformed traditional methods by increasing contrast ratios significantly and reducing computation time by up to 94-fold, suggesting it could be a valuable tool for clinical applications.
Modeling oxygen transport in the brain: An efficient coarse-grid approach to capture perivascular gradients in the parenchyma.
PLoS Comput Biol
May 2024
Institut de Mécanique des Fluides de Toulouse (IMFT), UMR 5502, Université de Toulouse, CNRS, Toulouse, France.
Recent progresses in intravital imaging have enabled highly-resolved measurements of periarteriolar oxygen gradients (POGs) within the brain parenchyma. POGs are increasingly used as proxies to estimate the local baseline oxygen consumption, which is a hallmark of cell activity. However, the oxygen profile around a given arteriole arises from an interplay between oxygen consumption and delivery, not only by this arteriole but also by distant capillaries.
View Article and Find Full Text PDFHigh-fidelity intravoxel incoherent motion parameter mapping using locally low-rank and subspace modeling.
Neuroimage
April 2024
Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA; Department of Imaging Sciences, University of Rochester, Rochester, NY, USA; Department of Physics and Astronomy, University of Rochester, Rochester, NY, USA. Electronic address:
Purpose: Intravoxel incoherent motion (IVIM) is a quantitative magnetic resonance imaging (MRI) method used to quantify perfusion properties of tissue non-invasively without contrast. However, clinical applications are limited by unreliable parameter estimates, particularly for the perfusion fraction (f) and pseudodiffusion coefficient (D*). This study aims to develop a high-fidelity reconstruction for reliable estimation of IVIM parameters.
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