The object of the present research was to study the effect of recombinant interleukin-2 (Ronkoleikin) on immune system in children with acute hematogenous osteomyelitis of long cortical bones. The investigation was conducted on 13-15 year old 30 patients with acute hematogenous osteomyelitis of long cortical bones. It was found that Ronkoleukin in sick children with acute hematogenous osteomyelitis of long cortical bones leads to improvement in humoral immune system. The pro- and anti inflammatory cytokine content is normalized.

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