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Effect of anthocyanin rich black sugarcane on milk production and antioxidant capacity in lactating dairy cows.
Sci Rep
January 2025
School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima, 30000, Thailand.
This study aimed to explore the effect of anthocyanin-rich black sugarcane on milk production, plasma antioxidant capacity, and the storage period DPPH scavenging capacity of milk in lactating dairy cows. Sixteen lactating dairy cows were stratified and randomly assigned into two balanced dietary groups, namely Anthocyanin-rich black sugarcane (AS), and Napier grass (NG). The AS group demonstrated a significant decrease (p < 0.
View Article and Find Full Text PDFPiezoelectric biosensor with dissipation monitoring enables the analysis of bacterial lytic agent activity.
Sci Rep
January 2025
Department of Biochemistry, Faculty of Science, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.
Antibiotic-resistant strains of Staphylococcus aureus pose a significant threat in healthcare, demanding urgent therapeutic solutions. Combining bacteriophages with conventional antibiotics, an innovative approach termed phage-antibiotic synergy, presents a promising treatment avenue. However, to enable new treatment strategies, there is a pressing need for methods to assess their efficacy reliably and rapidly.
View Article and Find Full Text PDFCodeveloping a community-based, peer-led psychosocial support intervention to reduce stigma and depression among people with tuberculosis and their households in Indonesia: a mixed-methods participatory action study.
NPJ Prim Care Respir Med
January 2025
Centre for Tuberculosis Research, Departments of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK.
Evidence relating to peer support and community-based psychological and social (psychosocial) interventions to reduce stigma and depression among people with tuberculosis (TB) and their households is limited. This study aimed to engage with multisectoral stakeholders in Indonesia to co-develop a peer-led, community-based psychosocial intervention that is replicable, acceptable, and sustainable. We used a participatory action design and engaged key national, multisectoral stakeholders to ensure that the intervention co-design was relevant and appropriate to the TB health system and the sociocultural context of Indonesia.
View Article and Find Full Text PDFLactoferrin conjugated radicicol nanoparticles enhanced drug delivery and cytotoxicity in prostate cancer cells.
Eur J Pharmacol
January 2025
School of Biomedical Sciences, Faculty of Health, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia; Translational Research Institute, Queensland University of Technology, Brisbane, Australia; Centre for Genomics and Personalised Health, Queensland University of Technology, Brisbane, Queensland, Australia. Electronic address:
Pyruvate dehydrogenase kinase-1 (PDK1) plays a crucial role in cancer cell metabolism by regulating the glycolytic pathway. Although, inhibitors targeting PDK1 have been effective in inhibiting glycolysis in multiple cancers, their lack of selectivity leading to off-target effects limit their therapeutic benefit. Herein, we investigated the inhibitory potential of six PDK1 inhibitors on cellular proliferation, migration, and invasion of androgen-sensitive LNCaP and androgen-negative PC-3 prostate cancer cells.
View Article and Find Full Text PDFInvestigating cognitive-physical task interaction during self-paced cycling: a Granger Causality study.
Psychol Sport Exerc
January 2025
Mind Brain and Behavior Research Center, CIMCYC-UGR, University of Granada, Spain; Department of Experimental Psychology, University of Granada, Spain.
Self-pacing physical exercise is thought to rely on high-order cognitive processing (e.g., attentional control to monitor afferent cardiovascular feedback for exercise goals).
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