Aniridia associated with congenital aphakia and secondary glaucoma.

Indian J Ophthalmol

VST Center for Glaucoma Care, L.V. Prasad Eye Institute, Hyderabad, India.

Published: January 2010

We report a case of aniridia associated with congenital aphakia and secondary glaucoma. A 35-year-old male presented with aniridia, congenital aphakia and secondary glaucoma in both eyes. After an unsuccessful medical management, he underwent trabeculectomy with mitomycin C and anterior vitrectomy under local anesthesia in his left eye. Postoperatively, at the end of six months, intraocular pressure (IOP) in his left eye was controlled without medications. This case highlights the rare association of aniridia with congenital aphakia and secondary glaucoma.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712705PMC
http://dx.doi.org/10.4103/0301-4738.53061DOI Listing

Publication Analysis

Top Keywords

congenital aphakia
16
aphakia secondary
16
secondary glaucoma
16
aniridia associated
8
associated congenital
8
aniridia congenital
8
left eye
8
aniridia
4
congenital
4
aphakia
4

Similar Publications

Novel Intragenic and Genomic Variants Highlight the Phenotypic Variability in -Related Disease.

Genes (Basel)

December 2024

Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.

: Disruption of results in microphthalmia with linear skin lesions (MLS) characterized by microphthalmia/anophthalmia, corneal opacity, aplastic skin lesions, variable central nervous system and cardiac anomalies, intellectual disability, and poor growth in heterozygous females. Structural variants consisting of chromosomal rearrangements or deletions are the most common variant type, but a small number of intragenic variants have been reported. : Exome sequencing identified variants affecting .

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated the long-term outcomes of scleral fixation of aniridic black diaphragm intraocular lenses (BDIOL) in 38 eyes affected by aniridia and aphakia due to trauma or congenital conditions.
  • After an average follow-up of 28 months, there was a significant improvement in visual acuity, and patients reported reduced glare and photophobia, though some experienced complications like elevated intraocular pressure and corneal decompensation.
  • The findings suggest that scleral fixation of BDIOL is an effective solution for patients lacking capsular support, providing good vision quality with a low rate of complications, regardless of prior surgical history.
View Article and Find Full Text PDF

Two novel variants in associated with anophthalmia and congenital cystic eye.

Ophthalmic Genet

January 2025

Department of Ophthalmology, Unidade de Saúde Local de São João, Porto, Portugal.

Purpose: We present the case of a newborn with right anophthalmia, left congenital cystic eye, and two novel variants in the gene. This report provides a comprehensive discussion of the clinical presentation, management strategies, and long-term follow-up for this rare condition.

Methods: A thorough ophthalmic examination was performed.

View Article and Find Full Text PDF

Objective: Achieving near normal vision following unilateral congenital cataract surgery is possible but requires early surgery, optical correction and consistent patching. Patching is often challenging for children and their caregivers. The goal of these analyses is to examine the association between reported consistency in patching during the first year after surgery and visual acuity.

View Article and Find Full Text PDF

Purpose: The goal of these analyses is to provide evidence that can help parents and healthcare providers determine whether or not to continue occlusion therapy once a reliable measure of optotype acuity can be obtained in children who are born with a unilateral congenital cataract.

Design: Data from the Infant Aphakia Treatment Study (IATS) are used in a cohort design.

Participants: A total of 105 children who participated in the IATS and did not have a vision-threatening adverse event.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!