AI Article Synopsis
- Treatment of omega-epoxynitriles with hydroxylamine leads to the formation of cyclic aminonitrones in a straightforward, highly selective manner.
- The effectiveness and versatility of this reaction were tested through various examples.
- The resulting aminonitrone products can be further modified, making them valuable for additional chemical applications.
Article Abstract
Treatment of omega-epoxynitriles with hydroxylamine affords cyclic aminonitrones in a single step and with high stereoselectivity. The scope of this novel transformation was explored in a series of examples. The aminonitrone products were shown to be useful substrates for further selective elaboration.
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| http://dx.doi.org/10.1021/ol9010147 | DOI Listing |
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