We analyzed the behavior of the electric field in a focal plane consisting of a solid immersion lens (SIL), an air gap, and a measurement sample for radially polarized illumination in SIL-based near-field optics with an annular aperture. The analysis was based on the Debye diffraction integral and multiple beam interference. For SIL-based near-field optics whose NA is higher than unity, radially polarized light generates a smaller beam spot on the bottom surface of a SIL than circularly polarized light; however, the beam spot on the measurement sample is broadened with a more dominant transverse electric field. By introducing an annular aperture technique, it is possible to decrease the effects of the transverse electric field, and therefore the size of the beam spot on the measurement sample can be small. This analysis could have various applications in near-field optical storage, near-field microscopy, lithography at ultrahigh resolution, and other applications that use SILs for high resolution.
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http://dx.doi.org/10.1364/ol.34.001961 | DOI Listing |
Phytochem Anal
December 2024
Department of Chemistry, Colorado State University, Fort Collins, Colorado, USA.
Introduction: Phenolic compounds garner interest in developing medicines, nutraceuticals, and cosmeceuticals based on natural products. The quantity of phenolic compounds in a sample is commonly determined via spectrophotometry; however, this instrumented technique is relatively laborious and time consuming and requires a large amount of reagents.
Objective: This work aimed to develop a simple, point-of-need colorimetric sensor to rapidly determine total phenolic content (TPC) in tea extracts.
Taking into account phase-polarization interactions is crucial for the formation of spatially structured laser beams. The effects that arise in this context can lead to the modulation of individual field components and the transformation of the overall light field. In this study, we investigate the impact of phase and polarization distributions with radial dependencies in polar coordinates on the longitudinal component of laser beams passing through a transmissive spatial light modulator (SLM) based on twisted nematic liquid crystals.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Department of Physics, National Institute of Technology, Meghalaya, India. Electronic address:
Liquid crystal (LC) based biosensors offer a sensitive platform for detecting biomolecules due to their ability to respond to molecular interactions through changes in LC orientations. In this paper, we introduce a novel LC biosensor using 4-heptyl-4-biphenyl carbonitrile (7CB) to detect Bovine Serum Albumin (BSA). The interaction between BSA and 7CB was investigated using polarising optical microscopy (POM), molecular docking (MD), and Raman spectroscopy.
View Article and Find Full Text PDFFront Mol Neurosci
December 2024
State Key Laboratory of Optometry, Ophthalmology and Vision Science, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Neuronal radial migration is a fundamental process for cortical development, the disruption of which causes neurological and psychiatric dysfunctions. SLIT2 plays diverse functions in brain development and is a well-known axon guidance molecule. In this study, we investigated the radial migration of projection neurons in the developing cerebral cortex by knockdown (KD) of in mice.
View Article and Find Full Text PDFDev Biol
December 2024
Department of Cell and Developmental Biology, University College London, Gower Street, London, WC1E 6BT, UK. Electronic address:
Before radial symmetry-breaking of the blastoderm, the chick embryo is distinctly divided into a central area pellucida and a surrounding region, the area opaca. In this review, we focus on the area opaca and its functions. First, we survey current knowledge about how the area opaca is formed during the intrauterine period and how it sets up its initial tissue structure.
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