Background/aim: To protect susceptible subjects from exposure to horse allergen, a Swedish national report recommended a distance of at least 500 m between homes and stables and other areas with horses. The aim of this project was to study indoor and outdoor levels of horse allergen in relation to distance from stables and horse tracks.
Methods: Indoor and outdoor samples were collected with Petri dishes at 49 sites in different housing areas and near to a track for trotting horses. In the apartments, Petri dishes were placed on a bookshelf in the living room at a height of approximately 1.5 m. Outdoors, cages containing Petri dishes were attached to tree branches at various distances from the horse track.
Results: Six of 45 indoor samples had detectable levels of horse allergen, 3 of those despite the fact that no family member had had any contact with horses, and 16 of 26 outdoor samples were positive. Outdoors, allergen levels drop quickly when the distance from stables or horses increases. Further, the allergen level found at a distance of 45 m from a horse track was around 1% of the allergen level found at 1 m from the track.
Conclusions: Allergens dispersed from horses decline rapidly outdoors and are barely found indoors in homes. We support the view that indirect exposure to horses such as exposure from clothing of horse riders, should be taken into account when measures to protect susceptible people from undesired exposure to horse allergens are taken.
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http://dx.doi.org/10.1159/000226234 | DOI Listing |
J Asthma Allergy
March 2025
Department of Clinical Laboratory, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510120, People's Republic of China.
Objective: This study aimed to investigate the molecular sensitization patterns of cats, dogs, and horses in patients with cat and/or dog sensitization and the IgE cross-reactivity with other furry animals.
Methods: In 95 patients diagnosed with allergic diseases and sensitized to cats and/or dogs (confirmed by specific Immunoglobulin E (sIgE) ≥ 0.35 kU/L to crude cat and/or dog dander extracts), sIgE levels of cat components (Fel d 1/2/4), dog components (Can f 1/2/3/5), horse dander (Equ c 1), as well as allergens from cow, guinea pig, mouse, rat, rabbit, and chicken, were measured.
Int J Mol Sci
February 2025
Clinic of Allergology, Clinical Immunology and Internal Diseases, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 87-100 Toruń, Poland.
The domestic horse is the third most common source of animal allergens. Currently, five equine allergens have been classified (Equ c 1, 2, 3, 4, 6). Despite the apparently low exposure to allergens, equine allergy is still of great clinical importance.
View Article and Find Full Text PDFFront Allergy
September 2024
Clinical Immunology Group, Division of Neurological Sciences, Department of Clinical Research-VPH, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Introduction: Insect bite hypersensitivity (IBH) is an IgE-mediated allergic dermatitis of horses caused by bites of spp., sharing some common features with human atopic dermatitis. Allergen immunotherapy (AIT) using whole-body extracts has limited efficacy.
View Article and Find Full Text PDFPediatr Allergy Immunol
October 2024
Department of Allergy, Clinical Research Center for Allergy and Rheumatology, NHO Sagamihara National Hospital, Sagamihara, Kanagawa, Japan.
Front Immunol
September 2024
Institute of Immunology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany.
Introduction: Equine asthma (EA) is a common disease of adult horses with chronic respiratory pathology and common neutrophilic airway inflammation. It presents with hyperreactivity to hay dust components such as molds, and underlying dysregulated T cell responses have been suggested. Thus far, T cells have been analysed in EA with conflicting results and the antigen reactivity of T cells has not been demonstrated.
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