Background: Delirium is an important problem especially in older medical inpatients.
Objective: The authors asked whether delirium and its duration are associated with higher mortality in a 3-month follow-up period.
Method: In this prospective cohort study, inpatients age 65 and older were assessed every 48 hours with the Confusion Assessment Method.
Results: Of 542 patients enrolled, 192 (35.4%) developed delirium. After 3 months, mortality in the delirium cohort was 25.9%, and in the nondelirium cohort was 5.8%. Delirium was independently associated with mortality, and increased by 11% for every 48 hours of delirium.
Conclusion: Delirium and increased delirium durations are significantly associated with higher mortality.
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http://dx.doi.org/10.1176/appi.psy.50.3.234 | DOI Listing |
Pediatr Infect Dis J
October 2024
From the Section of Critical Care Medicine, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado.
Background: When coronavirus disease 2019 (COVID-19) mitigation efforts waned, viral respiratory infections (VRIs) surged, potentially increasing the risk of postviral invasive bacterial infections (IBIs). We sought to evaluate the change in epidemiology and relationships between specific VRIs and IBIs [complicated pneumonia, complicated sinusitis and invasive group A streptococcus (iGAS)] over time using the National COVID Cohort Collaborative (N3C) dataset.
Methods: We performed a secondary analysis of all prospectively collected pediatric (<19 years old) and adult encounters at 58 N3C institutions, stratified by era: pre-pandemic (January 1, 2018, to February 28, 2020) versus pandemic (March 1, 2020, to June 1, 2023).
CJC Open
December 2024
Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Background: The objective of this study was to assess the health outcomes for patients who present to the emergency department (ED) with cardiac chest pain after the implementation of an accelerated diagnostic protocol using a high-sensitivity troponin assay (hs-TnI).
Methods: This prospective before-after cohort study used population-based linked health administrative data for adult patients who presented to a Canadian urban ED with chest pain of suspected cardiac origin over a 2-year study period. The primary outcome was ED length of stay (LOS).
Indian J Orthop
January 2025
Department of Orthopaedics, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh 201310 India.
Background: Bone marrow aspirate concentrate (BMAC) is considered one of the biological treatments for knee osteoarthritis (KOA). Patient selection remains a key factor to ensure that optimal treatment benefit and body mass index (BMI) are one of the key factors to be considered. This study aims to evaluate the influence of obesity on the duration of treatment benefit of BMAC for KOA.
View Article and Find Full Text PDFJ West Afr Coll Surg
August 2024
Neurosurgery Unit, Department of Surgery, Korle-Bu Teaching Hospital, Accra, Ghana.
Background: Traumatic brain injury (TBI) is one of the common causes of long-term disabilities, with about 10 million deaths annually.
Objectives: Our aim is to compare the severity and outcomes of TBI between motorcycle and car accident victims.
Materials And Methods: A prospective cohort study focusing on TBI patients.
Can J Kidney Health Dis
December 2024
Division of Nephrology, Centre Hospitalier de l'Université de Montréal, QC, Canada.
Background: Acute kidney injury (AKI) occurs in up to 50% of cardiac surgical patients and is often hemodynamically mediated. Point-of-care ultrasound is a non-invasive tool that has the potential to characterize intrarenal hemodynamics and predict the risk of AKI.
Objectives: We aimed to determine the predictive characteristics of intrarenal arterial and venous Doppler markers for postoperative AKI in cardiac surgical patients.
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