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Non-invasive Lobular Neoplasia: Review and Updates.
Semin Diagn Pathol
March 2025
Department of Pathology, Baptist Hospital of Miami, Baptist Health System, Miami, FL, USA.
Non-invasive lobular neoplasia (LN) encompasses atypical lobular hyperplasia (ALH), classic lobular carcinoma in situ (CLCIS), florid lobular carcinoma in situ (FLCIS), and pleomorphic lobular carcinoma in situ (PLCIS). Lobular neoplasia is a neoplastic epithelial proliferation of the terminal duct lobular unit. A defining feature is discohesion due to the loss of E-cadherin, a protein that facilitates cell-to-cell adhesion.
View Article and Find Full Text PDFVulvar Cellular Angiofibroma With Cytologic Atypia and Sarcomatous Transformation: A Clinicopathologic Analysis.
Int J Gynecol Pathol
March 2025
Emory University Hospital, Atlanta, GA.
Cellular angiofibromas (CAFs) are benign mesenchymal neoplasms of the vulva and lower genitourinary tract. Although most cases are benign with excellent prognosis, data on CAFs with cytologic atypia (aCAF) and sarcomatous transformation (tCAF) is limited. We identified 13 vulvar CAFs comprising 4 aCAFs and 9 tCAFs.
View Article and Find Full Text PDFEmbracing the Transoral Parapharyngeal Space Surgery (TOPPSS).
Indian J Otolaryngol Head Neck Surg
February 2025
Department of ENT HNS, Army Hospital Research and Referral, New Delhi, 110010 India.
Transoral Parapharyngeal Space Surgery (TOPPSS) is often opted by surgeons for parapharyngeal tumors. But its broad implementation is curtailed by limited exposure and the potential for various complications to arise. In this article, authors have outlined the 'DK et al.
View Article and Find Full Text PDFNot one size fits all: a half-mask-based GKRS treatment for preservation of a scalp flap. Illustrative case.
J Neurosurg Case Lessons
March 2025
Department of Radiation Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Background: Implementing the thermoplastic mask as a treatment option in Gamma Knife radiosurgery (GKRS) has madethe discussion of the relative benefits of frame- or mask-based fixation for treatment a frequent occurence. Based on a case review, the authors discuss factors that need to be understood and considered by the treating team.
Observations: The authors describe the case of an 81-year-old patient with pleomorphic dermal sarcoma that extended to and infiltrated the dura mater, who underwent extensive resection requiring a skin flap.
Characteristics of the Corneal Endothelium in Elderly Adults with High Myopia.
Phenomics
December 2024
Eye Institute, Eye and Ear, Nose, and Throat Hospital, Shanghai Medical College, Fudan University, 83 Fenyang Rd, Shanghai, 200031 People's Republic of China.
This cross-sectional study aimed to investigate the corneal endothelial characteristics in elderly individuals with high myopia. We assessed corneal endothelial characteristics in 1065 eyes of 1065 elderly patients (549 highly myopic and 516 control eyes) using non-contact specular microscopy. Confirmation of suspected Fuchs endothelial corneal dystrophy (FECD) was performed with slit-lamp and confocal microscopy.
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