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In-vivo imaging of murine tumors using complete-angle projection fluorescence molecular tomography. | LitMetric

AI Article Synopsis

Article Abstract

We interrogate the ability of free-space fluorescence tomography to image small animals in vivo using charge-coupled device (CCD) camera measurements over 360-deg noncontact projections. We demonstrate the performance of normalized dual-wavelength measurements that are essential for in-vivo use, as they account for the heterogeneous distribution of photons in tissue. In-vivo imaging is then showcased on mouse lung and brain tumors cross-validated by x-ray microcomputed tomography and histology.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881930PMC
http://dx.doi.org/10.1117/1.3149854DOI Listing

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