Twenty-one healthy volunteers aged 21 to 37 years (21 eyes) were examined on a MP-1 microperimeter and a Humphrey HFA II-750i perimeter by the 10-2 program. The standard stimulation parameters used on the microperimeter revealed a wide plateau in the central visual field due to the limited stimulus intensity range of MP-1. The comparable data on both perimeters could be obtained only with small-sized stimuli (Goldmann I). However, quantitative comparison demonstrated significant differences in the reduction of differential light thresholds from 2 degrees to 10 degrees from the fixation point. The studies have indicated that the technical characteristics of the MP-1 microperimeter does not allow one to elaborate algorithms for recounting the data to compare with those obtained on the Humphrey perimeter. It has been ascertained that the MP-1 microperimeter should not be used to solve the problems of conventional computed perimetry.
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Arch Rehabil Res Clin Transl
December 2024
Section of Neurorehabilitation, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Nystagmus has various clinical manifestations, including downbeat, upbeat, and torsional types, each associated with distinct neurologic features. Current rehabilitative interventions focusing on fixation training and optical correction often fail to achieve complete resolution. When nystagmus coexists with fragile X-associated tremor/ataxia syndrome (FXTAS), functional impairments worsen, particularly affecting balance.
View Article and Find Full Text PDFSci Rep
July 2024
Ophthalmic Department, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany.
In order to determine the effect of nystagmus on objective visual acuity (VA) estimates, we compared subjective (VA) and objective (VEP, VA) VA estimates in participants with nystagmus. For this purpose, 20 participants with nystagmus (NY) caused by idiopathic infantile nystagmus, albinism, achiasma or acquired nystagmus were recruited in this study. Estimates of BCVA (best corrected visual acuity) were determined psychophysically (VA; FrACT, Freiburg visual acuity test) and electrophysiologically (VA; EP2000) according to ISCEV (International Society of Clinical Electrophysiology of Vision) guidelines.
View Article and Find Full Text PDFPurpose: This study assesses the effect of pleoptic treatment on the stability of visual fixation in children and adolescents with amblyopia of various degrees.
Material And Methods: The effect of the treatment in 35 children (35 eyes) with amblyopia of various degrees was evaluated using the MP-1 Microperimeter. The stability was determined by two criteria - number of fixation point hits in the 2° zone and the width of the field of fixation.
Ophthalmol Sci
June 2023
Byers Eye Institute, Stanford University School of Medicine, Palo Alto, California.
Purpose: To assess different microperimetry (MP) macular sensitivity outcome measures capturing functional deterioration in eyes with geographic atrophy (GA) secondary to age-related macular degeneration (AMD).
Design: Patients were included from 2 identically designed, phase III, double-masked, randomized controlled clinical trials, Chroma (NCT02247479) and Spectri (NCT02247531).
Participants: Patients enrolled were aged ≥ 50 years with bilateral GA and no evidence of previous or active neovascular AMD.
Most sources state that pleoptic treatment is ineffective after the age of 14 years. Despite the high level of diagnostic capabilities in modern ophthalmology, unilateral amblyopia is quite often diagnosed in adolescents. This rises the question - should they refuse treatment? To evaluate the impact of treatment on retinal light sensitivity and the state of the patient's visual fixation, a 23-year-old female patient with high degree amblyopia was examined using the MP-1 Microperimeter.
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