Objective: To investigate the detection rate of impaired fasting glycaemia (IFG), the prevalence of diabetes mellitus (DM) and related risk factors, the current situation on awareness, treatment and the rate of control on diabetes mellitus in residents living in Nangang district of Harbin city, Heilongjiang province.
Methods: A cross-sectional cluster sampling was carried out in residents aged over 35 years, living in Fendou community of Harbin city.
Results: Data from 3017 out of 3183 residents were analyzed. In men, women and overall residents, the detection rates of IFG were 5.38%, 2.44% and 3.75%, respectively. After standardization, the detection rates became 5.41%, 2.18% and 3.59%, respectively. The prevalence rates of DM were 12.40%, 8.46%, 10.21% and 11.80%, 8.20% and 9.77%, before and after standardization. Results showed statistical difference between age, sex and levels of fasting glycaemia. Data from single factor analysis revealed that smoking, BMI, hypertension and high triglyceride were risk factors on the levels of high fasting glycaemia. Results from multivariable stepwise analysis showed that sex, age, BMI, hypertension and high triglyceride were significant factors influencing the levels of high fasting glycaemia with the OR (95% CI) is 1.546 (1.250-1.912), 1.308 (1.171-1.461), 1.038 (1.010-1.066), 1.388 (1.106-1.741) and 1.700 (1.370-2.110), respectively. The rates on awareness, treatment and control in DM were 73.38%, 59.42% and 36.36% respectively. Among those who had knowledge on DM, the rates on treatment and on control were 80.97% and 61.20%.
Conclusion: Our results showed that the prevalence of DM was high in the communities and it is essential to further increase the awareness, treatment and control rates on DM.
Download full-text PDF |
Source |
---|
Diabet Med
January 2025
Universidad Científica del Sur, Lima, Peru.
Background And Aims: Impaired glucose intolerance (IGT) and impaired fasting glucose (IFG) are totally different. Lifestyle modification is effective in moving from prediabetes to normoglycaemia. There is a lack of information showing the effect of lifestyle modification according to each prediabetes and assessing its effect on the degree of reversibility to normoglycaemia and on cardiometabolic markers.
View Article and Find Full Text PDFClin Sci (Lond)
December 2024
Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Chronic inflammatory diseases, e.g., obesity, cardiovascular disease, and type 2 diabetes, progressively suppress the anti-inflammatory heat shock response (HSR) by impairing the synthesis of key components, perpetuating inflammation.
View Article and Find Full Text PDFDiabetes Obes Metab
December 2024
Sanofi Investment Co., Ltd., Shanghai, China.
Aims: To evaluate the efficacy and safety of insulin glargine 300 U/mL (Gla-300) in people with uncontrolled type 2 diabetes (T2D) switching from another basal insulin (BI).
Materials And Methods: INITIATION was an interventional, single-arm, phase IV study conducted in China. In this post hoc subpopulation analysis, the efficacy and safety of switching to Gla-300 was investigated in individuals with uncontrolled T2D (HbA1c 7.
Diabetes Obes Metab
February 2025
Univ. Lille, CHU Lille, Inserm U1190, EGID, Institut Pasteur de Lille, Lille, France.
Objective: Although primarily secreted by the liver, Fibroblast Growth Factor 21 (FGF21) is also expressed in the pancreas, where its function remains unclear. This study aims to elucidate the role of the glucagon-FGF21 interaction in the metabolic benefits of SGLT2 inhibition (SGLT2i) and hypothesizes it is key to enhancing glucose and lipid metabolism in individuals with glucose intolerance or type 2 diabetes (T2D).
Methods: FGF21, FGF1R, and β-klotho expression in human pancreas was analysed by RNAscope, qPCR and immunofluorescent techniques.
Diabetes Obes Metab
November 2024
Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto, Ontario, Canada.
Aims: When administered in early type 2 diabetes (T2DM), the strategy of 'induction' with short-term intensive insulin therapy (IIT) followed by 'maintenance' with metformin thereafter can yield outstanding glycaemic control, with some patients achieving A1c in the normal range of its assay. We thus sought to identify determinants of sustained normalisation of A1c in response to this treatment strategy.
Materials And Methods: In this study, adults with T2DM of mean duration 1.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!