AI Article Synopsis
- Oxaliplatin is commonly used to treat colorectal cancer but can cause rare side effects, including renal failure and hemolytic reactions.
- A case is presented showing a patient who experienced immune-related hemolysis and acute tubular necrosis while on oxaliplatin.
- This situation offers insights into how oxaliplatin may lead to kidney failure in some patients.
Article Abstract
Oxaliplatin is an effective chemotherapeutic agent frequently used in the treatment of colorectal carcinoma. Rare cases of renal failure and hemolytic reactions have been reported as separate side effects of oxaliplatin. Here we present a clinical picture of immune-related intravascular hemolysis and acute tubular necrosis in a patient receiving this drug. This case suggests a mechanistic explanation of renal failure in patients treated with oxaliplatin.
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| http://dx.doi.org/10.1007/s12032-009-9263-3 | DOI Listing |
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