AI Article Synopsis
- A study was conducted to evaluate the effectiveness of splenic autotransplantation combined with lower esophagus transaction anastomosis in treating portal hypertension due to liver cirrhosis.
- Thirty-six patients were randomly assigned to either the splenic autotransplantation group or a control group that only underwent splenectomy, and various health markers were monitored before and after the procedures.
- Results showed that patients in the splenic autotransplantation group had significantly higher levels of immune markers compared to the control group two months post-surgery, indicating it may help preserve immune function.
Article Abstract
Objective: To study the therapeutic effect of splenic autotransplantation combined with lower esophagus transaction anastomosis in the treatment of liver cirrhosis induced portal hypertension.
Methods: Thirty-six patients admitted from January 2003 to December 2006 were randomly divided into splenic autotransplantation group undergoing splenic autotransplantation after splenectomy combined with lower esophagus transaction anastomosis, and splenectomy group only undergoing splenectomy combined with lower esophagus transaction anastomosis. The general conduction, splenic scanning, liver function, and the level of serum Tuftsin and IgM of each patient were observed before and after operation.
Results: The levels of Tuftsin and IgM in splenic autotransplantation group were significant higher than that of splenectomy group 2 months after the operation, and the liver function showed no significant difference between these two groups. Splenic tissue was detected in the retroperitoneal space by 99mTc-DRBC 2 months after operation.
Conclusions: Splenic autotransplantation combined with lower esophagus transaction anastomosis is a safe and effective treatment strategy for patients with liver cirrhosis induced portal hypertension, and the spleen tissue transplanted into the retroperitoneal space can partially preserve the immune function.
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