Bis-anthracenyl isoxazolyl amides have enhanced anticancer activity.

Bioorg Med Chem Lett

Department of Biomedical and Pharmaceutical Sciences, The University of Montana, Missoula, MT 59812, USA.

Published: August 2009

Dimeric analogs of Anthracenyl Isoxazole Amides (AIMs) (the designation AIM is in honor of the memory of Professor Albert I. Meyers) were prepared and dimer 6 exhibited the highest efficacy to date for this class of anti-tumor compounds against the human glioma Central Nervous System cell line SNB-19.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731571PMC
http://dx.doi.org/10.1016/j.bmcl.2009.06.019DOI Listing

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Bis-anthracenyl isoxazolyl amides have enhanced anticancer activity.

Bioorg Med Chem Lett

August 2009

Department of Biomedical and Pharmaceutical Sciences, The University of Montana, Missoula, MT 59812, USA.

Dimeric analogs of Anthracenyl Isoxazole Amides (AIMs) (the designation AIM is in honor of the memory of Professor Albert I. Meyers) were prepared and dimer 6 exhibited the highest efficacy to date for this class of anti-tumor compounds against the human glioma Central Nervous System cell line SNB-19.

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