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Staphylococcal Scalded Skin Syndrome, Identification, and Wound Care: A Case Report Series.
Adv Neonatal Care
August 2022
Neonatal Intensive Care Unit, TriHealth, Good Samaritan Hospital, Cincinnati, Ohio (Ms McKeown); and Nursing Administration, TriHealth, Cincinnati, Ohio (Dr Baker).
Introduction: Methicillin-susceptible Staphylococcus aureus (MSSA) infections cause diseases ranging from localized skin infections to serious invasive infections. Neonates are immunosuppressed, placing them at increased risk for MSSA infections, including staphylococcal scalded skin syndrome (SSSS), a rare severe skin presentation of MSSA.
Clinical Findings: We present a case series of 3 preterm infants with SSSS receiving care at a level 3 neonatal intensive care unit.
Development and clinical validation of loop-mediated isothermal amplification (LAMP) assay to diagnose high HBV DNA levels in resource-limited settings.
Clin Microbiol Infect
December 2021
Unité d'Epidémiologie des Maladies Émergentes, Institut Pasteur, Paris, France. Electronic address:
Objective: A massive scale-up of testing and treatment is indicated to globally eliminate hepatitis B virus (HBV) infection. However, access to a polymerase chain reaction (PCR), a key test to quantify HBV DNA levels and determine treatment eligibility, is limited in resource-limited countries. We have developed and evaluated the loop-mediated isothermal amplification (LAMP) assay to diagnose clinically important HBV DNA thresholds defined by the WHO (≥20 000 and ≥ 200 000 IU/mL).
View Article and Find Full Text PDFSevere infections of Panton-Valentine leukocidin positive Staphylococcus aureus in children.
Medicine (Baltimore)
September 2019
Department of Pediatric Pneumology, Immunology and Intensive Care.
Infections caused by Panton-Valentine leukocidin-positive Staphylococcus aureus (PVL-SA) mostly present as recurrent skin abscesses and furunculosis. However, life-threatening infections (eg, necrotizing pneumonia, necrotizing fasciitis, and osteomyelitis) caused by PVL-SA have also been reported.We assessed the clinical phenotype, frequency, clinical implications (surgery, length of treatment in hospitals/intensive care units, and antibiotic treatments), and potential preventability of severe PVL-SA infections in children.
View Article and Find Full Text PDFNeck carbuncle associated with methicillin-susceptible bacteraemia.
BMJ Case Rep
October 2018
Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.
Clinical and histopathological features of Burkholderia cepacia complex dermatitis in dogs: a series of four cases.
Vet Dermatol
October 2018
Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey St, Philadelphia, PA, 19104, USA.
Article Synopsis
- The Burkholderia cepacia complex (Bcc) is a rising cause of opportunistic infections in dogs, particularly those on immunosuppressive medications.
- A study examined four dogs with Bcc-related dermatitis, highlighting diverse clinical symptoms and severe histopathological findings, including significant inflamed skin conditions.
- Treatment varies, with most dogs responding to certain antibiotics, though one case developed severe sepsis and resistance, ultimately leading to euthanasia.
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