Objective: To investigate the effect of preterm birth, the time of birth, and birth hospital level and district on health-related quality of life (HRQoL) and quality-adjusted life years (QALYs).
Study Design: This national study included all very low birth weight infants (VLBWIs; birth weight
Results: HRQoL at age 5 years was lower and 1.3 QALYs were lost in VLBWIs compared with controls. Regional differences in the QALYs of VLBWIs were found among the 5 university hospital districts. Birth hospital level or birth outside office hours had no effect on the QALYs of live-born VLBWIs. The adjusted HRQoL total score was not affected by birth outside office hours or by the birth hospital level or district.
Conclusions: Differences in QALYs related to hospital district suggest variation in the care of VLBWIs that needs to be addressed.
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