[Unstable angina pectoris: outcomes of acute period and determinative factors].

Aim: To follow up for 28 days outcomes of unstable angina (UA) and to determine factors affecting the disease course and negative potential of these factors.

Material And Methods: Basing on UA clinical manifestations, 1477 patients aged 20-70 years observed in Tomsk in 2003-2004 were divided into 4 groups: group 1--patients with angina of new onset; group 2--patients with more frequent angina attacks; group 3--patients with more frequent and more severe angina attacks (longer, more painful, attacks at rest, less effective arrest with nitroglycerin); group 4--20 min and longer anginal attacks).

Results: On the disease day 29 UA stabilization was achieved in 1096 (74.12%) patients, UA exacerbation without acute coronary pathology (acute myocardial infarction or acute coronary insufficiency) was seen in 7 (0.47%) patients, 375 (25.41%) UA patients had acute myocardial infarction. The greatest number of acute coronary episodes (51.3%) occurred in group 1 patients. Myocardial infarction developed least frequently in group 4 patients (3.3%).

Conclusion: Clinical symptoms of UA, ECG ischemic changes and diabetes mellitus are factors of UA unfavourable outcome.