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A false positive for metastatic lymph nodes in the axillary region of a breast cancer patient following mastectomy. | LitMetric

AI Article Synopsis

  • Advanced imaging techniques like PET using 18-FDG are valuable in detecting cancers and informing treatment, but can sometimes yield false positives.
  • A 48-year-old breast cancer patient had tumors mistakenly identified as malignant lymph nodes through PET/CT and ultrasound, but they turned out to be benign schwannomas after surgical removal.
  • It highlights the need for caution as imaging methods may not always accurately distinguish between benign and malignant lesions, especially in post-mastectomy patients.

Article Abstract

Recent advanced imaging modalities such as positron emission tomography (PET) detect malignancies using 2-[18F]-fluoro-2-deoxy-D: -glucose (18-FDG) with high accuracy, and they contribute to decisions regarding diagnosis, staging, recurrence, and treatment response. Here, we report a case of false-positive metastatic lymph nodes that were diagnosed by PET/CT and ultrasonography in a 48-year-old breast cancer patient who had undergone mastectomy. The tumors, which were oval shaped and resembled lymph nodes, were detected by ultrasonography. PET/CT revealed high uptake of 18-FDG in the tumors. To investigate the proposed recurrence and to re-evaluate the biology of the recurrent tumors, a tumor was removed from the brachial plexus of the patient. Histological findings revealed it to be a schwannoma. All imaging modalities including PET/CT failed to distinguish benign tumors from metastatic lymph nodes in the brachial plexus. After resection of the schwannomas, the patient complained of a slight motor disorder of the second finger on the right hand. Hence, it is important to consider a false-positive case of lymph node metastasis in a breast cancer patient following mastectomy.

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Source
http://dx.doi.org/10.1007/s12282-009-0125-9DOI Listing

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