Background: Ganglia are the most common benign soft tissue tumours of the hand. Although benign, a significant number of patients with wrist ganglia consult with their general practitioners, and ultimately the hand surgeon, complaining of pain. A great number of patients are concerned about the cosmetic appearance, and an equally significant number genuinely believe that the ganglion is a cancer. There are several management options resulting in varying degrees of success. These include observation only, surgical excision, aspiration only, aspiration with injection of methylprednisolone, and aspiration with injection of methylprednisolone and hyaluronidase.
Objective: The main objective was to investigate the effectiveness and safety of sodium tetradecyl sulfate as a sclerosing agent after aspiration of wrist ganglia.
Methods: Initial data were collected prospectively during a period of 48 months. Following this, patients were sent a postal survey at least two years after they had received treatment to access the levels of recurrence and persistent complications.
Results: In the short term, 90% of the patients achieved complete resolution after one episode of aspiration and injection. However, there was only a 65% cure rate after two to five years. Complications were few and not significant.
Conclusion: Sodium tetradecyl sulfate is an effective sclerosing agent after aspiration of wrist ganglia with an excellent short-term efficacy and a long-term cure rate comparable to that of surgical excision.
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http://dx.doi.org/10.1177/229255030601400112 | DOI Listing |
Cureus
November 2024
Department of Oral and Maxillofacial Surgery, Meghna Institute of Dental Sciences, Nizamabad, IND.
Vascular malformations (VMs) are congenital abnormalities of blood or lymphatic vessels, present at birth and growing proportionally with the individual. They are classified into types such as capillary, venous, lymphatic, and arteriovenous malformation (AVMs). Symptoms include discoloration, swelling, pain, or functional impairment, depending on the type and location.
View Article and Find Full Text PDFJ Phys Chem B
January 2025
Surfactant Chemistry Laboratory, Department of Chemistry, The University of Burdwan, Burdwan 713104, West Bengal, India.
The oxidation kinetics of phenylalanine (Phe) by Ce(IV) have been examined in both the absence and presence of aqueous micellar media with asymmetric tails, specifically using sodium dodecyl sulfate (SDS) and sodium tetradecyl sulfate (STS) surfactants. The reaction progress was monitored by observing a decrease in absorbance using UV-vis spectroscopy. Interestingly, the kinetic profile revealed a consistent increase in the observed rate constant values as the concentration of the surfactant increased.
View Article and Find Full Text PDFACS Omega
December 2024
Universidade Federal da Paraíba, Núcleo de Pesquisa e Extensão - Laboratório de Combustíveis e Materiais (NPE - LACOM), Cidade Universitária s/n - Campus I, 58051-900 João Pessoa, PB, Brazil.
Diclofenac is an emerging contaminant widely detected in water and has had adverse effects on the biota. In this study, the adsorbents were prepared by reacting tetradecyl-(C), hexadecyl-(C), and octadecyltrimethylammonium (C) bromides with sodium vermiculite (Na-Ver) and used for the removal of the first time for diclofenac sodium from aqueous solution. Synthesis was carried out in a microwave-assisted reactor operating at 50 °C for 5 min, using proportions of organic salts in 100 and 200% of the phyllosilicate cation exchange capacity.
View Article and Find Full Text PDFAm J Otolaryngol
December 2024
Department of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, 660 S Euclid Ave, CB 8115, St. Louis, MO 63110, USA; Clinical Outcomes Research Office, Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, 660 S Euclid Ave, CB 8115, St. Louis, MO 63110, USA. Electronic address:
Background: Hereditary hemorrhagic telangiectasia (HHT) is characterized by abnormal blood vessel formation. One treatment for HHT-related arteriovenous malformations (AVMs) is sclerotherapy, which collapses the blood vessels by irritating the endothelial lining.
Methods: This case series describes two HHT patients undergoing in-office sodium tetradecyl sulfate sclerotherapy for non-nasal telangiectasias and AVMs.
CVIR Endovasc
November 2024
George's Healthcare NHS Trust, St George's University Hospitals NHS Foundation Trust, London, SW17 0QT, UK.
Purpose: To propose a standardized method of subjectively and objectively evaluating outcomes of sclerotherapy in treating low flow vascular malformations.
Materials And Methods: Sixty-six patients with low flow vascular malformations (venous, lymphatic, or combined) were treated with percutaneous sclerotherapy using bleomycin, doxycycline, or sodium tetradecyl sulphate. Each lesion required between 2-5 sessions of sclerotherapy with 8-week intervals in between.
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