Intralesional amphotericin B in a cat with refractory localised sporotrichosis.

J Feline Med Surg

Laboratory of Clinical Research on Dermatozoonosis in Domestic Animals, Evandro Chagas Clinical Research Institute/Oswaldo Cruz Foundation (Fiocruz), Av Brasil, 4365 - Manguinhos, 21045-900, Rio de Janeiro - RJ, Brazil.

Published: August 2009

The present report concerns a case of sporotrichosis in a 3-year-old male crossbred cat. After 9 months of oral itraconazole (20mg/kg) therapy, all skin lesions had resolved with the exception of a single nodular lesion located on the bridge of the nose. Therefore, a combined therapy that included intralesional (IL) amphotericin B (1mg/kg) was started. The lesion resolved completely after three weekly administrations of IL amphotericin B, given in concert with oral itraconazole. The cat remains well 1 year after discontinuing therapy, with no signs of recurrence.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11132565PMC
http://dx.doi.org/10.1016/j.jfms.2009.01.012DOI Listing

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