The difficulty to keep our patients' skin intact combined with few articles on this topic in pediatrics led the authors to carry out a study in their Pediatrics Intensive Care Unit "UCIP" at the Central University Hospital of Asturias, HUCA. The objective of this study consisted in determining if a decrease in the appearance of bed sores in children checked into their unit after a program whose purpose was to prevent bed sores had been applied occurred. This retrospective/prospective, comparative, observational study dealt with patients checked in their UCIP from September 2004 to September 2007; patients were broken into two groups, before and after applying a protocol and comparing the following variables: the number of patients checked in during each of the periods of this study; patients who had bed sores; average time kept in this ward for each group; pathologies patients who suffered from bed sores had when checked into this ward; the site and degree of these bed sores. Although there was an increase in the number of patients checked into this unit, the number of bed sores among children in this unit decreased 24.6% during the second period after the application of the protocol. Among the study observations noted there was a reduction in the severity of lesions patients manifested, as well as important differences as to where their lesions were located. Based on the results of the authors' study, one may conclude that the measures included in the bed sore prevention protocol, as well as the use of Mepentol hyperoxygenated fatty acids, have proven effective in their UCIP leading to a decrease in the number of patients which evidenced bed sores and the severity of these lesions was much less.
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Biosensors (Basel)
November 2024
Department of Chemistry, University of Waterloo, 200 University Ave West, Waterloo, ON N2L 3G1, Canada.
Hypoxia, characterized by inadequate tissue oxygenation, may result in tissue damage and organ failure if not addressed. Current detection approaches frequently prove insufficient, depending on symptoms and rudimentary metrics such as tissue oxygenation, which fail to comprehensively identify the onset of hypoxia. The European Pressure Ulcer Advisory Panel (EPUAP) has recognized sweat lactate as a possible marker for the early identification of decubitus ulcers, nevertheless, neither sweat lactate nor oxygenation independently provides an appropriate diagnosis of hypoxia.
View Article and Find Full Text PDFPlast Reconstr Surg Glob Open
December 2024
Britecyte, Inc., Frederick, MD.
Background: Loss or displacement of a fat pad on the foot increases plantar pressure, leading to pain and plantar ulcers. These ulcers, especially in patients with diabetic neuropathy, have high recurrence rates, often resulting in amputations. Standard of care focuses on reducing plantar pressure with shoe padding or orthotic devices, leaving the restoration of the fat pad as an unmet medical need.
View Article and Find Full Text PDFActa Diabetol
December 2024
Azienda Sanitaria Friuli Occidentale, Pordenone, Italy.
Aim: To assess the effects of several adjuvant therapies (AT) commonly used in the treatment of diabetic foot ulcers (DFU). The present meta-analysis was designed to support the development of the Italian Guidelines for the Treatment of Diabetic Foot Syndrome.
Methods: A Medline and Embase search were performed up to May 20th, 2024 collecting all RCTs including diabetic patients or reporting subgroup analyses on diabetic patients with DFU comparing AT with placebo/standard of care (SoC), with a duration of at least 12 weeks.
"Wound, Pressure Ulcer, and Burn Guidelines-5: Guidelines for the management of lower leg ulcers and varicose veins, second edition" is revised from the first edition, which was published in the Japanese Journal of Dermatology in 2011. The guidelines were drafted by the Wound, Pressure Ulcer, and Burn Guidelines Drafting Committee delegated by the Japanese Dermatological Association and intend to facilitate physicians' clinical decisions in preventing, diagnosing and management of lower leg ulcers and varicose veins. We updated all sections by collecting documents published since the publication of the first edition.
View Article and Find Full Text PDFRadiology
December 2024
From the Department of Radiology, Mayo Clinic Arizona, 5777 E Mayo Blvd, Phoenix, AZ 85054.
History A 65-year-old male patient with a history of sarcomatoid renal cell carcinoma and prior right nephrectomy developed recurrent disease adjacent to the inferior vena cava. The patient underwent surveillance imaging 7 months after initiation of treatment with maximum-dose pazopanib and less than 1 month after completing a 2-month regimen of palliative stereotactic body radiation therapy to the right nephrectomy bed and site of recurrence. (Stereotactic body radiation therapy was initiated 5 months after pazopanib treatment was initiated.
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