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Serial intrauterine transfusion for severe fetal anemia due to anti-M alloimmunization.

Asian J Transfus Sci

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Department of Obstetrics and Gynecology, Faculty of Medicine Padjajaran University, Hasan Sadikin General Hospital, Bandung, Indonesia.

Anti-M antibody is one of the causes of severe fetal anemia and intrauterine death despite its relatively low frequency. A G3P2 26-year-old pregnant woman referred to our hospital at 29 weeks gestational age (WGA) with fetal hydrops. Her second pregnancy results in intrauterine fetal death at 35 WGA due to fetal hydrops.

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Background: Constrictive pericarditis (CP) can arise from various causes, including post-operative degeneration, tuberculosis, and sequelae of pericarditis. Immunoglobulin (Ig) G4-related disease is a rare but recognized cause of CP. However, the specific mechanisms underlying these aetiologies and pathologies remain unclear.

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Article Synopsis
  • Chronic constrictive pericarditis (CCP) is a disease marked by the thickening of the pericardium, leading to heart function issues, with a focus on patient demographics and clinical profiles in Northeast India over a decade.
  • The study analyzed 42 CCP patients between 2011 and 2020, highlighting a high prevalence in younger individuals and a significant history of tuberculosis among participants.
  • Symptoms included dyspnea and physical exam findings such as edema and hepatomegaly; imaging revealed notable heart structural changes, emphasizing the need for better diagnosis and management in the region.
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