Oocyte recovery post human follicular fluid centrifugation in modified natural cycle and achieving embryo.

Reprod Biomed Online

Département de Médecine et Biologie de la Reproduction, Hôpital Arnaud de Villeneuve, Université Montpellier I, UFR de Médecine, INSERM U, France.

Published: May 2009

AI Article Synopsis

  • * The modified natural cycle involved centrifugation of human follicular fluid (HFF) to retrieve oocytes, resulting in the collection of two viable oocytes when initially only one was visible.
  • * The technique of HFF centrifugation led to the formation of two embryos without compromising their quality, ultimately leading to a live birth in April 2008.

Article Abstract

This case reports a successful live birth by intracytoplasmic sperm injection (ICSI) following human follicular fluid (HFF) centrifugation for oocyte retrieval in the modified natural cycle of a poor responder patient. A 37-year-old patient presenting with a severe ovarian defect underwent a modified natural cycle with HFF centrifugation prior to ICSI. As there was only one oocyte under direct binocular observation, HFF was centrifuged and a second oocyte was collected. ICSI was performed on both oocytes. Embryo quality and outcome were not compromised by HFF centrifugation. A live birth was achieved in April 2008. In a modified natural cycle, HFF centrifugation avoided loss of oocytes, optimized the IVF treatment, and achieved the development of two embryos.

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Source
http://dx.doi.org/10.1016/s1472-6483(10)60012-0DOI Listing

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