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Neurologic manifestations of Chagas disease.

Curr Neurol Neurosci Rep

December 2011

Hospital Universitario Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rua Marechal Mascarenhas de Moraes, 191/408 Copacabana, Rio de Janeiro, Brazil.

Chagas disease is endemic in Latin America and has become an emerging problem in developed countries because of international migrations. The protozoan Trypanosoma cruzi is the etiologic agent and the disease is divided into two phases. The acute phase is mostly asymptomatic or presents with unspecific symptoms.

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Background: Patients with AIDS frequently show secondary involvement of the brain by different infectious agents, and Chagas' disease is now recognized as a potential opportunistic infection. To our knowledge, pseudotumoral chagasic meningoencephalitis has not been previously reported as the first manifestation of AIDS.

Methods And Results: A 30-year-old Argentinian man without any risk factor for HIV infection was admitted to the hospital with an acute onset of drowsiness.

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