Objective: To identify hantavirus from lung specimens of rats captured in Guangxi.

Methods: Rats were collected from various areas in Guangxi in combination with plague surveillance and rat lung specimens were examined by ELISA for hantavirus antigen, and M segment of positive specimen was partially amplified with RT-PCR and sequenced. Phylogenetic analysis was conducted for genotyping.

Results: From a total of 306 rat lung specimens, a strain of SEO hantavirus was detected from lung specimen of a Norvegicus that was from coastal area of Guangxi Qinzhou city.

Conclusions: For the first time SEO hantanvirus was detected in the coastal area of Guangxi Qinzhou city, its epidemiological significance needs further study.

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