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Alzheimer Disease as a Clinical-Biological Construct-An International Working Group Recommendation.
JAMA Neurol
December 2024
Laboratory of Neuroimaging of Aging, University of Geneva, Geneva, Switzerland.
Article Synopsis
- * Concerns are raised about purely biological definitions being used in clinical settings, especially since many biomarker-positive but cognitively normal individuals may never develop symptoms, complicating diagnosis and patient understanding.
- * The authors advocate for a combined clinical-biological definition of AD that accommodates at-risk and presymptomatic stages, emphasizing the need for caution in diagnosing AD without fully understanding the implications for patients.
Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury: The TRAIN Randomized Clinical Trial.
JAMA
November 2024
Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Importance: Blood transfusions are commonly administered to patients with acute brain injury. The optimal hemoglobin transfusion threshold is uncertain in this patient population.
Objective: To assess the impact on neurological outcome of 2 different hemoglobin thresholds to guide red blood cell transfusions in patients with acute brain injury.
On the road to exercise as medicine for depressive symptoms in young people.
Transl Pediatr
July 2024
Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.
Volatile Sedation with Sevoflurane After Aneurysmal Subarachnoid Hemorrhage Using the Sedaconda Anesthetic Conserving Device: Is It Safe?
Neurocrit Care
August 2024
Department of Anesthesiology and Intensive Care Medicine, Jessa Hospital, Hasselt, Belgium.
Racial/Ethnic Disparities in Pregnancy-Associated Death: The Critical Importance of Disaggregation by Cause of Death and Race/Ethnicity.
Am J Public Health
July 2024
Clare C. Brown is with the Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock. Dominique DuBois is with the College of Nursing, University of Arkansas for Medical Sciences.
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