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http://dx.doi.org/10.1136/bmj.303.6808.995-c | DOI Listing |
J Mater Sci Mater Med
January 2025
Clinic of Prosthetic Dentistry and Biomedical Materials Research, Hannover Medical School, Hannover, Germany.
Although implants have undergone a remarkable development over the past decades, modern implants still show complications that make the improvement of materials necessary. The presented study investigates the load-bearing capacity of an experimental dental implant made of a niobium alloy (Nb1Zr) compared to identical implants made of Ti6Al4V using chewing simulation for artificial aging. Eight implants each with an experimental design were manufactured from Nb1Zr and Ti6Al4V.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
January 2025
Department of Growth and Development, Capital Institute of Pediatrics, Beijing, China.
Context: Bone age assessment (BAA) is critical for pediatric endocrinology. Traditional methods are complex and time-consuming, and current computer-aided systems have made progress but still lacking in robustness.
Objective: Develop simplified BAA methods to aid pediatricians in quick clinical assessments.
Med Chem
January 2025
Department of Chemistry and Biochemistry, Faculty of Medicine and Pharmacy, Ibn Zohr University, Laayoune 70000, Morocco.
Background: Oxidative stress is strongly linked to neurodegeneration through the activation of c-Abl kinase, which arrests α-synuclein proteolysis by interacting with parkin interacting substrate (PARIS) and aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 (AIMP2). This activation, triggered by ataxia-telangiectasia mutated (ATM) kinase, leads to dopaminergic neuron loss and α-synuclein aggregation, a critical pathophysiological aspect of Parkinson's disease (PD). To halt PD progression, pharmacological inhibition of c-Abl kinase is essential.
View Article and Find Full Text PDFExtracell Vesicles Circ Nucl Acids
December 2024
Department of Otorhinolaryngology, Head and Neck Surgery, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong 00000, China.
Current approaches to oral cancer diagnosis primarily involve physical examination, tissue biopsy, and advanced computer-aided imaging techniques. However, despite these advances, patient survival rates have not significantly improved. Hence, there is a critical need to develop minimally invasive tools with high sensitivity and specificity to improve patient survival and quality of life.
View Article and Find Full Text PDFiScience
January 2025
The First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan 250013, P.R. China.
The advancement of information technology and AI has boosted global economic and social development. Robot systems (RS) and computer-aided technology (CAT) are used in various domains, including social production and human existence. Traditional fracture reduction surgery relies on the expertise and surgical skills of surgeons to realign fractures in patients.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!