This article surveys the current situation and prospects for attaining the goals set by the International Conference on Population and Development (ICPD) held in 1994, and the health-related Millennium Development Goals (MDGs), set in 2000. Encouraging changes in the policy environment are highlighted, but the available resources do not yet match needs. Global maternal mortality figures, at over 500,000 a year, have not changed since 1990, and morbidity is about 20 million. Some countries have made progress with low-cost, high-yield interventions such as family planning, skilled birth attendants, access to emergency obstetric and neonatal care, management of sexually transmitted infections, and HIV prevention. However, progress in many low-income countries has been slow, and few are on track to meet the goals. There are wide inequities in care among and within countries. Suggestions for priority attention are offered, such as a "continuum of care" approach, integrated services, and comprehensive policies on human resources for health.
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http://dx.doi.org/10.1016/j.ijgo.2009.03.017 | DOI Listing |
Rheumatol Ther
January 2025
Saitama Medical University, 38 Morohongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan.
Introduction: Ozoralizumab (OZR) is a novel tumor necrosis factor (TNF) inhibitor that was launched in Japan for treating patients with rheumatoid arthritis (RA) who have had an inadequate response to existing therapies. This post-hoc analysis aimed to compare the efficacy of OZR administered without methotrexate (MTX) with placebo or OZR administration in combination with MTX.
Methods: We analyzed the OZR group (30 mg) in the NATSUZORA trial (non-MTX, open trial) (OZR group; n = 94) and the placebo group (MTX group; n = 75) and the 30-mg OZR group (OZR + MTX group; n = 152) in the OHZORA trial (combined MTX, double-blind trial), and the covariates were adjusted by propensity score matching.
Int J Chron Obstruct Pulmon Dis
January 2025
School of Translational Medicine, Monash University, Melbourne, VIC, Australia.
Purpose: Oral corticosteroids (OCS) are recommended for the treatment of exacerbations in people with COPD; however, high cumulative lifetime doses (≥1000mg prednisolone-equivalent) are associated with adverse health effects. This issue is well defined in asthma but is less well understood in COPD. The aim of this study was to examine cumulative OCS dispensed to people with COPD over 12 months.
View Article and Find Full Text PDFJ Obsessive Compuls Relat Disord
July 2024
Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School.
The Yale-Brown Obsessive-Compulsive Scale modified for Body Dysmorphic Disorder (BDD-YBOCS) is a semi-structured interview designed to assess the severity of current BDD. The aim of the study was to examine the factor structure and construct validity of the BDD-YBOCS. The sample included 366 adults with BDD who completed the BDD-YBOCS and other measures of BDD severity/impairment, psychiatric distress (i.
View Article and Find Full Text PDFBiochem Pharmacol
January 2025
Department of Biology, Acadia University, Wolfville, NS, Canada.
Updates Surg
January 2025
Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Clinical risk prediction models are ubiquitous in many surgical domains. The traditional approach to develop these models involves the use of regression analysis. Machine learning algorithms are gaining in popularity as an alternative approach for prediction and classification problems.
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