Although intramuscular triamcinolone acetonide has been available as a dermatologic therapy for many years, it is used sparingly or not at all by many dermatologists because of concern about its safety, as well as a lack of understanding of its specific therapeutic benefits. This case report discusses the efficacy and safety of intramuscular triamcinolone acetonide, along with description of the specific technique employed by the author, as well as the clinical indications and side effects seen by the author in his practice over time. The report describes the positive results attained in the treatment of many chronic, recalcitrant dermatologic conditions that cannot be adequately controlled by topical therapy alone. Because of its strong safety profile and unique therapeutic efficacy, intramuscular triamcinolone should be considered as a primary therapy for many chronic, steroid responsive, dermatologic conditions requiring a systemic approach.
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Rheumatol Adv Pract
December 2024
Department of Anesthesiology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Objectives: Rotator cuff tendinitis (RCT) is a tendon inflammation often following subacromial impingement syndrome. One of the non-surgical management modalities for RCT is subacromial injection of corticosteroids. Some studies have claimed a correlation between ACTH (Adrenocorticotropic Hormone) deficiency and rotator cuff lesions; hence, intramuscular ACTH analogue injection has been recommended as an option.
View Article and Find Full Text PDFAm J Respir Crit Care Med
November 2024
National Jewish Health, Denver, Colorado, United States;
Rationale: Corticosteroid-responsive type 2 (T2) inflammation underlies the T2-high asthma endotype. However, we hypothesized that type 1 (T1) inflammation, possibly related to viral infection, may also influence corticosteroid response.
Objectives: To determine the frequency and within-patient variability of T1-high, T2-high, and T1/T2-high asthma endotypes and whether virally influenced T1-high disease influences corticosteroid response in asthma.
Immune checkpoint inhibitors have revolutionised the treatment of cancer. While very effective, they commonly cause a wide spectrum of immune-related adverse events. These immune-related adverse events can be fatal and often have significant effects on quality of life.
View Article and Find Full Text PDFIndian J Dermatol Venereol Leprol
October 2023
Dermosphere Clinic, Dwarka, New Delhi, India.
Background Isolated nail lichen planus (NLP) without mucocutaneous involvement is rare. Literature about the clinical profile and management is scarce. Aims/Objective We attempted to characterize the clinico-demographic profile and analyze the management outcome of patients with isolated nail lichen planus.
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