Small large-cell neuroendocrine carcinoma in a patient with pulmonary emphysema.

Tuberk Toraks

Divisions of Respiratory Medicine, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-city, Ibaraki, Japan.

Published: October 2009

Large-cell neuroendocrine carcinomas (LCNECs) are relatively rare, and most reported occurrences tend to involve relatively large tumors. We report a small LCNEC in a 63-year-old male patient with pulmonary emphysema. The peripheral pulmonary nodule did not have lobulation and spiculation, and it was difficult to establish correct diagnosis before surgery because of its small size and effect of surrounding emphysematous change.

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