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A Unique Case of Infected Laryngeal Tophi With Underlying Gout.
Cureus
November 2024
Otolaryngology - Head and Neck Surgery, Hospital Queen Elizabeth, Kota Kinabalu, MYS.
Gout is a disorder of purine metabolism described by the deposition of monosodium urate crystals with rare involvement in the head and neck. This is the first laryngeal gout case reported in Sabah, Malaysia. A 50-year-old gentleman with a long history of gouty arthritis presented with acute painless anterior neck swelling for two weeks.
View Article and Find Full Text PDFRefractory Tophaceous Gout With Psoriatic Arthritis: A Case Report.
Cureus
November 2024
Internal Medicine, Unidade Local de Saúde de Santo António, Porto, PRT.
Although gout is a common intermittent crystalline arthropathy, tophaceous gout is a rare condition. Flares of this disease are usually treated with anti-inflammatory drugs followed by control of serum uric acid levels. We present a refractory, severe, tophaceous gout overlapping with psoriatic arthritis, presenting with a hyper-inflamed phenotype resistant to conventional anti-inflammatory and hypouricemic agents.
View Article and Find Full Text PDFClinical Images: Osteomyelitis complicating uncommon tophaceous gout: a case study with genetic findings.
ACR Open Rheumatol
January 2025
Radiology Unit, Santa Maria della Scaletta Hospital, Imola, Italy.
Bone Erosions and Systemic Bone Loss on HR-pQCT in Men With Tophaceous Gout.
Int J Rheum Dis
December 2024
Division of Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, São Paulo, Brazil.
Aims: Gout, a prevalent inflammatory arthropathy, predominantly affects males and arises from persistent hyperuricemia, resulting in monosodium urate crystal deposition. Hyperuricemia is associated with comorbidities, exacerbating patient morbidity. Conflicting literature exists regarding uric acid's impact on bone mineral density (BMD), with potential proinflammatory effects in gout patients.
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