Objective: We examined the interventions and outcomes of pre-term patients with an incidentally identified fetal heart rate (FHR) deceleration and otherwise reassuring FHR pattern admitted for continuous FHR monitoring (FM).
Methods: A case series was compiled of patients with at least 36 h of continuous FM secondary to a FHR deceleration. Data on demographics, delivery and perinatal outcomes, medical and obstetric history were extracted from medical records. FHR tracings were reviewed for quantity and type of decelerations.
Results: Ninety-seven patients met inclusion criteria. The median length of time monitored was 4 days with a median of four decelerations a day. Fifty-eight percent of patients were delivered during the same admission primarily for a non-reassuring FHR tracing with a mean delivery gestational age of 33.7 weeks. Patients with resolution of their decelerations delivered at a mean gestational age of 35.8 weeks. No patients with a resolution of decelerations presented later with an intrauterine fetal demise.
Conclusion: Although it is possible that FHR decelerations were markers for adverse outcomes, none of the infants delivered for decelerations had an abnormal cord gas. Because it may lead to pre-term delivery based on false positive testing, clinicians should use caution when prescribing prolonged FM.
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http://dx.doi.org/10.1080/14767050802556059 | DOI Listing |
BMC Pregnancy Childbirth
December 2024
College of Health Science, Department of Midwifery, Arsi University, Asella, Ethiopia.
Background: The World Health Organization recommends a cesarean delivery rate of 5-15%, which is thought to be within the range that can reduce infant morbidity and mortality. Various investigations have shown that those poor newborn outcomes are influenced by a variety of maternal and fetal factors and are more prevalent in emergencies than planned cesarean deliveries. Ethiopia is one of the five nations that account for 50% of all neonatal fatalities worldwide.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
December 2024
Department of Obstetrics and Gynecology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Purpose: To determine the reference values for the shock index (SI) in postpartum patients undergoing elective cesarean delivery with regional anesthesia.
Methods: This prospective study was conducted at our tertiary center between August 1, 2023, and March 1, 2024. We calculated the reference values for the SI within the first 48 h postpartum for patients who underwent elective cesarean delivery after the 34th week of gestation.
Cytotherapy
December 2024
Molecular and Clinical Hematology Branch, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA.
Sickle cell disease (SCD) is the most common inherited blood disorder worldwide, impacting millions and imposing severe healthcare challenges, particularly in resource-limited regions. Current treatments have variable efficacy and require lifelong adherence. Allogeneic Hematopoietic Stem Cell Transplantation can be curative but comes with significant side effects and limited donor availability limits its widespread applicability.
View Article and Find Full Text PDFMed Sci (Basel)
December 2024
Department of Perinatology, Ege University, İzmir 35000, Turkey.
Objective: This study aims to investigate the possible effects of gestational diabetes mellitus (GDM) on fetal heart structure and the relationship of this effect with maternal blood sugar control.
Materials And Methods: In this cross-sectional study, 19 women with GDM at 24-36 weeks of gestation (case group) and 21 healthy pregnant women at the same weeks of gestation (control group) were examined. Fetal heart structure was evaluated by ultrasonography; interventricular septum (IVS) thickness, right and left ventricular sphericity indices, global sphericity index (GSI) and cardio-thoracic ratio were also measured.
Circ Res
December 2024
Cardiovascular Research Center, Massachusetts General Hospital, Boston. (C.C., P.X., Z.Y., Y.S., E.S.L., J.D.R., M.C.H.).
Background: Preeclampsia is a hypertensive disorder of pregnancy characterized by systemic endothelial dysfunction. The pathophysiology of preeclampsia remains incompletely understood. This study used human venous endothelial cell (EC) transcriptional profiling to investigate potential novel mechanisms underlying EC dysfunction in preeclampsia.
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