Based on the results of a fully vectorial finite-difference analysis, we identify three important regimes of field-profile and dispersion management of photonic-crystal fibers with a solid core modified by arrays of nanosize air-hole defects. In the first regime, very small air holes act as weak perturbations, slightly modifying the field profiles of fiber modes and red-shifting the wavelength of zero group-velocity dispersion (GVD). In the second regime, larger holes reduce the effective mode area, tightening the confinement of the light field in the fiber core and blue-shifting the zero- GVD wavelength. Finally, in the third regime, the nanosize air-hole defects with diameters above a critical value induce a phase-transition-type behavior of mode field profiles, dramatically reducing the localization of the field in the fiber core and increasing the radiation power in the fiber cladding. This phase transition in mode field profiles qualitatively modifies the wavelength dependence of the effective mode area and dispersion parameters of fiber modes, especially in the long-wavelength range, suggesting an attractive strategy for fiber dispersion and mode area engineering.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1364/oe.14.010878 | DOI Listing |
Electrophoresis
January 2025
Institute of Forensic Science, Fudan University, Shanghai, P. R. China.
The human skin and oral cavity harbor complex microbial communities, which exist in dynamic equilibrium with the host's physiological state and the external environment. This study investigates the microbial atlas of human skin and oral cavities using samples collected over a 10-month period, aiming to assess how both internal and external factors influence the human microbiome. We examined bacterial community diversity and stability across various body sites, including palm and nasal skin, saliva, and oral epithelial cells, during environmental changes and a COVID-19 pandemic.
View Article and Find Full Text PDFEur J Nucl Med Mol Imaging
January 2025
Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave., Wuhan, Hubei, 430022, China.
As the smallest antibody fragment with specific binding affinity, nanobody-based nuclear medicine has demonstrated significant potential to revolutionize the field of precision medicine, supported by burgeoning preclinical investigations and accumulating clinical evidence. However, the visualization of nanobodies has also exposed their suboptimal biodistribution patterns, which has spurred collaborative efforts to refine their pharmacokinetic and pharmacodynamic profiles for improved therapeutic efficacy. In this review, we present clinical results that exemplify the benefits of nanobody-based molecular imaging in cancer diagnosis.
View Article and Find Full Text PDFSci Rep
January 2025
Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ, 07102, USA.
In vitro studies have shown that a neuron's electroresponsive properties can predispose it to oscillate at specific frequencies. In contrast, network activity in vivo can entrain neurons to rhythms that their biophysical properties do not predispose them to favor. However, there is limited information on the comparative frequency profile of unit entrainment across brain regions.
View Article and Find Full Text PDFAnal Chim Acta
February 2025
School of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao, 066004, PR China; Hebei Key Laboratory of Micro-Nano Precision Optical Sensing and Measurement Technology, Qinhuangdao, 066004, PR China. Electronic address:
Background: Fractionation of microalgal cells has important applications in producing pharmaceuticals and treating diseases. Multiple types of microalgal cells generally coexist in the oceans or lakes and are easily contaminated by microplastics and bacteria. Therefore, it is of paramount significance to develop an effective fractionation approach for microalgal cells for biological applications.
View Article and Find Full Text PDFAnal Chim Acta
February 2025
Faculty of Chinese Medicine & State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macau, China. Electronic address:
Background: Carbohydrates exhibit diverse functions and extensive biological activities and are notable in the field of life sciences. However, their inherent diversity and complexity-steaming from variations in isomeric monomers, glycosidic bonds, configurations, etc.-present considerable challenges in structural analysis.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!