We propose a compact laser configuration based on resonating both the pump and signal light along a microfiber ring doped with active ions. We estimate the minimum Q-factor to obtain lasing and find that values already demonstrated in passive microfiber rings will be sufficient. We model the performance of this device in steady state using rate equations and show that pump resonance can significantly reduce the threshold and increase the quantum efficiency, especially for rings made of materials with weak active ion absorption. Numerical examples for erbium and ytterbium doped devices are presented. Taking into account scattering and coupling losses the optimum pump coupling factor is calculated. The dependences of the quantum efficiency and threshold power on the coupling losses are also investigated. We predict that efficient ytterbium-doped lasers can be obtained with a ring diameter down to a few tens of micrometers.
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http://dx.doi.org/10.1364/oe.14.007073 | DOI Listing |
J Biomed Mater Res A
January 2025
Shu Chien-Gene Lay Department of Bioengineering, University of California San Diego, La Jolla, California, USA.
Conventional two-dimensional (2D) cardiomyocyte differentiation protocols create cells with limited maturity, which impairs their predictive capacity and has driven interest in three-dimensional (3D) engineered cardiac tissue models of varying maturity and scalability. Cardiac spheroids are attractive high-throughput models that have demonstrated improved functional and transcriptional maturity over conventional 2D differentiations. However, these 3D models still tend to have limited contractile and electrical maturity compared to highly engineered cardiac tissues; hence, we incorporated a library of conductive polymer microfibers in cardiac spheroids to determine if fiber properties could accelerate maturation.
View Article and Find Full Text PDFACS Appl Mater Interfaces
November 2024
Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.
Surface modification of materials with proteins has various biological applications, and hence the methodology for surface modification needs to accommodate a wide range of proteins that differ in structure, size, and function. Presented here is a methodology that uses the Affinity Bioorthogonal Chemistry (ABC) tag, 3-(2-pyridyl)-6-methyltetrazine (PyTz), for the site-selective modification and purification of proteins and subsequent attachment of the protein to -cyclooctene (TCO)-functionalized hydrogel microfibers. This method of surface modification is shown to maintain the functionality of the protein after conjugation with proteins of varying size and functionalities, namely, HaloTag, NanoLuc luciferase (NanoLuc), and fibronectin type III domains 9-10 (FNIII 9-10).
View Article and Find Full Text PDFBiosens Bioelectron
January 2025
Department of Physics and Electrical Engineering, Northumbria University, Newcastle upon Tyne, NE1 8ST, United Kingdom; Key Laboratory for Optoelectronic Information Perception and Instrumentation of Jiangxi Province, Nanchang Hangkong University, Nanchang 330063, China. Electronic address:
Squamous cell carcinoma antigen (SCCA) is one of the most commonly detected cancer biomarkers for a variety of cancers. In this paper, a microfiber ring laser biosensor with a graphene oxide linking layer for SCCA detection was proposed and experimentally demonstrated. SCCA antibody immobilized on graphene oxide surface binds specifically to SCCA, and induces refractive index variation over the surface of the microfiber biosensor, which leads to a wavelength shift of the microfiber ring laser biosensor.
View Article and Find Full Text PDFSmall
November 2024
Department of Materials Science and Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-ro, Nam-gu, Pohang, 37673, Republic of Korea.
Among the lead halide perovskite (LHP) family, CsPbI is known to be significantly vulnerable to moisture, which hinders its use in real device applications. It is reported that chalcogen-based ligands can better stabilize CsPbI and revive nanocrystals (NCs). Here, diphenyl diselenide (DPhDSe) ligand is used to revive the degraded CsPbI NCs through a post-synthetic treatment of adding a small amount of DPhDSe in the degraded NC dispersion.
View Article and Find Full Text PDFMaterials (Basel)
February 2023
Department of Materials, Fibers and Textile Testing, Faculty of Textile Technology, University of Zagreb, Prilaz baruna Filipovića 28a, 10000 Zagreb, Croatia.
Socks, being a necessary item of clothing, must be comfortable and maintain their quality throughout their life. Since the applicability of modal fibers and microfibers, as well as yarns produced using unconventional processes, in sock knitting has been insufficiently researched, this paper evaluated three groups of medium sized socks knitted in a plain single jersey pattern produced with the highest percentage of ring, rotor and air-jet spun modal or micro modal yarns of the same linear density in full plating with different textured polyamide 6.6 yarns compared to conventional cotton socks.
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