Characterization of the plasmid-borne quinolone resistance gene qnrB19 in Salmonella enterica serovar Typhimurium.

Antimicrob Agents Chemother

Istituto Superiore di Sanità, Department of Infectious, Parasitic and Immuno-Mediated Diseases, Viale Regina Elena 299, 00161 Rome, Italy.

Published: September 2009

A qnrB19 gene variant, carried by an IncL/M-like plasmid, was detected in a multidrug Salmonella enterica serovar Typhimurium human strain with reduced susceptibility to ciprofloxacin. The genetic environment around the gene was fully sequenced (20 kb). A large gene cluster, containing the aph, qnrB19, and blaSHV-12-like resistance genes, is inserted inside a Tn3 transposon.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737868PMC
http://dx.doi.org/10.1128/AAC.00294-09DOI Listing

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