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Neural speech tracking contribution of lip movements predicts behavioral deterioration when the speaker's mouth is occluded.
eNeuro
January 2025
Paris-Lodron-University of Salzburg, Department of Psychology, Centre for Cognitive Neuroscience, Salzburg, Austria
Observing lip movements of a speaker facilitates speech understanding, especially in challenging listening situations. Converging evidence from neuroscientific studies shows stronger neural responses to audiovisual stimuli compared to audio-only stimuli. However, the interindividual variability of this contribution of lip movement information and its consequences on behavior are unknown.
View Article and Find Full Text PDFCompletely conserved VP2 residue K140 of KREMEN1-dependent enteroviruses is critical for virus-receptor interactions and viral infection.
mBio
January 2025
Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, China.
Unlabelled: The KREMEN1 (KRM1) protein is a cellular receptor for multiple enteroviruses that cause hand, foot, and mouth disease (HFMD), including coxsackievirus CVA2, CVA3, CVA4, CVA5, CVA6, CVA10, and CVA12. The molecular basis for the broad recognition of these viruses by the KRM1 receptor remains unclear. Here, we report the indispensable role of the completely conserved VP2 capsid protein residue K140 (designated K2140) in mediating receptor recognition and infection by CVA10 and other KRM1-dependent enteroviruses.
View Article and Find Full Text PDFMaximal mouth opening in infants and toddlers with spinal muscular atrophy: a prospective controlled study.
Orphanet J Rare Dis
January 2025
Department of Voice, Speech and Hearing Disorders, University Dysphagia Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Background: Bulbar function is frequently impaired in patients with spinal muscular atrophy (SMA). Although extremely important for the patient's quality of life, it is difficult to address therapeutically. Due to bulbar dysfunction, maximum mouth opening (MMO) is suspected to be reduced in children with SMA.
View Article and Find Full Text PDFAccuracy evaluation and clinical realization of digital interproximal enamel reduction for orthodontics: a case study.
Biomed Eng Online
January 2025
College of Mechanical Engineering, Zhejiang University of Technology, Hangzhou, 310023, China.
Objective: This study presents a novel digital interproximal enamel reduction (IER) clinical procedure, aiming to improve the effectiveness of IER processes in orthodontic treatment.
Methods: A malocclusion case of skeletal-class I and angle-class I was selected for the experimental investigation. A three-dimensional (3D) model of the dentition was constructed using scanning data from a plaster model.
[Controlling cystic echinococcosis: outlook in the 21st centuryControle da equinococose/hidatidose cística: perspectivas no século XXI].
Rev Panam Salud Publica
January 2025
Centro Panamericano de Fiebre Aftosa Unidad de Salud Pública Veterinaria Organización Panamericana de la Salud Río de Janeiro Brasil Centro Panamericano de Fiebre Aftosa, Unidad de Salud Pública Veterinaria, Organización Panamericana de la Salud, Río de Janeiro, Brasil.
Cystic echinococcosis (CE) is a serious public health problem in South America, one that the Pan American Health Organization (PAHO) has included in its Plan of Action for the Control of Neglected Infectious Diseases. A logical framework for CE control was defined: this includes establishing the objective to be achieved (eradication or elimination as a public health problem) and determining levels of endemicity which serve as a guide for establishing frequencies of intervention (high endemicity, endemic, and low endemicity, according to rates in the different hosts). There are two validated tools for CE control: systematic deworming of dogs using praziquantel (PZQ) and systematic vaccination of sheep with recombinant EG95 protein, or a combination of both tools.
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