AI Article Synopsis
- For the first time, SOMO activation has been used to enable a new method for alpha-chlorination of aldehydes.
- This new process integrates well with a linchpin catalysis strategy.
- It allows for the efficient and enantioselective production of terminal epoxides.
Article Abstract
Time for SOme MOre: For the first time SOMO (singly occupied molecular orbital) activation has been exploited to allow a new approach to the alpha-chlorination of aldehydes. This transformation can be readily implemented as part of a linchpin catalysis approach to the enantioselective production of terminal epoxides.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439133 | PMC |
| http://dx.doi.org/10.1002/anie.200901855 | DOI Listing |
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